{"id":"W2084347203","doi":"10.1067/msy.2003.246","title":"Hypertonic resuscitation of hemorrhagic shock upregulates the anti-inflammatory response by alveolar macrophages","year":2003,"lang":"en","type":"article","venue":"Surgery","topic":"Trauma, Hemostasis, Coagulopathy, Resuscitation","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto General Hospital; University of Toronto; University Health Network","funders":"","keywords":"Medicine; ARDS; Hypertonic saline; Resuscitation; In vivo; Lipopolysaccharide; Ex vivo; Proinflammatory cytokine; Tumor necrosis factor alpha; Immunology; Alveolar macrophage; Cytokine; Pharmacology; Bronchoalveolar lavage; Macrophage; Lung; Inflammation; In vitro; Anesthesia; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002845771,0.0004951481,0.0004783748,0.0003888363,0.0002456169,0.0004702877,0.0001310962,0.0002987669,0.001843869],"category_scores_gemma":[0.0004018879,0.0002106289,0.0003607059,0.0001434426,0.0002835001,0.0003016355,0.0003987831,0.0007186884,0.0004873493],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000190424,"about_ca_system_score_gemma":0.0002336904,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001905018,"about_ca_topic_score_gemma":0.0002414449,"domain_scores_codex":[0.999574,0.0001543205,0.00003431444,0.00003194129,0.00006990658,0.0001354729],"domain_scores_gemma":[0.9996718,0.00007295126,0.00008146517,0.00004669566,0.00005681396,0.00007024719],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002545625,0.0002646397,0.001267695,0.0001236608,0.00002633525,0.0003467405,0.0001094923,0.0001648545,0.9849936,0.0002167325,0.0004257112,0.009514971],"study_design_scores_gemma":[0.0006426338,0.00735455,0.1305138,0.0001406076,0.0001998807,0.001598808,0.00106928,0.002416227,0.8457544,0.0008668108,0.009390851,0.00005209547],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99159,0.004116139,0.001014252,0.0004463955,0.0001244839,0.00004826584,0.0001172292,0.00004983431,0.002493464],"genre_scores_gemma":[0.994612,0.001999994,0.0007415746,0.0002582635,0.0001720898,0.00006583311,0.0002214618,0.00001355342,0.001915298],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001843869,"threshold_uncertainty_score":0.006168365,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01396422190385427,"score_gpt":0.2462740605345802,"score_spread":0.2323098386307259,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}