{"id":"W2084401256","doi":"10.1016/j.dci.2005.06.018","title":"Antibodies, immunoglobulin genes and the bursa of Fabricius in chicken B cell development","year":2005,"lang":"en","type":"review","venue":"Developmental & Comparative Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":271,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada Research Chairs; Sunnybrook Health Science Centre; Women's College Hospital; University of Toronto","funders":"","keywords":"Biology; Immunoglobulin class switching; Antibody; Immunoglobulin heavy chain; Allelic exclusion; Immunoglobulin gene; Immunoglobulin D; Gene rearrangement; Bursa of Fabricius; B cell; Immunoglobulin light chain; Surface Immunoglobulin; Gene conversion; Immunoglobulin G; Molecular biology; Gene; Pseudogene; Antibody Repertoire; Genetics; Immune system; Allele; T cell; T-cell receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004327414,0.0008308744,0.0008322817,0.001255319,0.0002683375,0.0007824271,0.0009770441,0.001112957,0.001613551],"category_scores_gemma":[0.000275589,0.0004055628,0.0001689454,0.001325187,0.0007953812,0.001146779,0.0005105399,0.001005397,0.001180421],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007618339,"about_ca_system_score_gemma":0.000682339,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002033675,"about_ca_topic_score_gemma":0.003172731,"domain_scores_codex":[0.9999151,0.000008579664,0.00001387135,0.0000256582,0.00002730226,0.000009470195],"domain_scores_gemma":[0.9998616,0.00004050877,0.00003169631,0.000004546489,0.00004021347,0.00002141828],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000259424,0.00004390185,0.0006895262,0.007978047,0.00005961803,0.0007300462,0.0001160679,0.0008027744,0.02882522,0.006447789,0.02357934,0.9304683],"study_design_scores_gemma":[0.00003461649,0.0001030943,0.003774952,0.001195466,0.0001201898,0.001811159,0.0001411537,0.0002060871,0.004329003,0.002494273,0.9857692,0.00002079813],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001083607,0.9964716,0.0003913139,0.0002189009,0.0003887164,0.000003660666,0.00001755095,0.00000915242,0.00141548],"genre_scores_gemma":[0.004154206,0.9914019,0.0004547245,0.0002362153,0.0004288706,0.000006906563,0.000066272,0.000002264915,0.003248721],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002033675,"threshold_uncertainty_score":0.005527556,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04123123087668091,"score_gpt":0.2945577491701378,"score_spread":0.2533265182934569,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}