{"id":"W2084401256","doi":"10.1016/j.dci.2005.06.018","title":"Antibodies, immunoglobulin genes and the bursa of Fabricius in chicken B cell development","year":2005,"lang":"en","type":"review","venue":"Developmental & Comparative Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":271,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada Research Chairs; Sunnybrook Health Science Centre; Women's College Hospital; University of Toronto","funders":"","keywords":"Biology; Immunoglobulin class switching; Antibody; Immunoglobulin heavy chain; Allelic exclusion; Immunoglobulin gene; Immunoglobulin D; Gene rearrangement; Bursa of Fabricius; B cell; Immunoglobulin light chain; Surface Immunoglobulin; Gene conversion; Immunoglobulin G; Molecular biology; Gene; Pseudogene; Antibody Repertoire; Genetics; Immune system; Allele; T cell; T-cell receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0007952922,0.001284455,0.004917059,0.000745535,0.0004723047,0.00003354809,0.001393026,0.001237891,0.0005543449],"category_scores_gemma":[0.00003653234,0.000892822,0.0004084816,0.0006620329,0.003283476,0.0001308152,0.00129033,0.001714444,0.001175587],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004382641,"about_ca_system_score_gemma":0.00115382,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003079704,"about_ca_topic_score_gemma":0.0002029066,"domain_scores_codex":[0.9933029,0.001765539,0.002634851,0.001067897,0.0001094339,0.001119371],"domain_scores_gemma":[0.9968412,0.001056,0.001337867,0.0006006206,0.0001309093,0.00003339272],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0009216053,0.0010693,0.0002945865,0.001669606,0.004322174,0.00004328775,0.01002414,0.000001692289,0.03046745,0.001175918,0.0007514186,0.9492588],"study_design_scores_gemma":[0.005094551,0.0001349579,0.0003523948,0.001516735,0.0003051158,0.000714329,0.001426275,3.956726e-7,0.01768996,0.00003076864,0.9717749,0.0009596082],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02361878,0.9706661,0.00001448653,0.00004207889,0.0009154386,0.001747323,0.00006036587,0.00006484098,0.002870625],"genre_scores_gemma":[0.03239653,0.9623483,0.0008221197,0.00005164954,0.00003180739,0.0003885307,0.0008503384,0.00006638463,0.003044312],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9710235,"threshold_uncertainty_score":0.9999907,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04123123087668091,"score_gpt":0.2945577491701378,"score_spread":0.2533265182934569,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}