{"id":"W2084408282","doi":"10.1089/10445490050128430","title":"Cooperative Binding of TEF-1 to Repeated GGAATG-Related Consensus Elements with Restricted Spatial Separation and Orientation","year":2000,"lang":"en","type":"article","venue":"DNA and Cell Biology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Biology; Consensus sequence; Enhancer; Binding site; DNA binding site; Transcription factor; DNA; Molecular biology; Oligonucleotide; Gene; Transcription (linguistics); Genetics; Peptide sequence; Promoter; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004991968,0.00009484104,0.0001125535,0.00003414854,0.00006001469,0.000007958008,0.00003150821,0.0001087728,0.00002659318],"category_scores_gemma":[0.000008030886,0.00008014864,0.00001069382,0.00007736788,0.00007063367,0.000001300917,0.00002090079,0.00003401026,0.000002277415],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005643821,"about_ca_system_score_gemma":0.0000264076,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005660273,"about_ca_topic_score_gemma":0.00004554764,"domain_scores_codex":[0.9993837,0.00004425968,0.0001933688,0.0002366564,0.00002792006,0.0001141225],"domain_scores_gemma":[0.9997204,0.000007571509,0.00007496058,0.0000935377,0.00005723132,0.00004628664],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002162905,0.00002530395,0.01106206,0.000006615071,0.00003138529,0.000001185067,0.0001581882,0.00009097243,0.9848276,0.00003318919,0.00003305772,0.003514177],"study_design_scores_gemma":[0.003712395,0.004490161,0.02405514,0.00002284795,0.00007556941,0.00003190714,0.0004083093,0.003342237,0.9593766,0.00005342685,0.00400481,0.0004266275],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986019,0.00006724105,0.0001223188,0.00002561795,0.0000300347,0.0001963706,0.0000461923,0.000004870794,0.0009055089],"genre_scores_gemma":[0.9983974,0.00014144,0.0004182263,0.00003580401,0.00001311176,0.000007163774,0.0006101715,0.000007449976,0.0003692068],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02545101,"threshold_uncertainty_score":0.3268366,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003904322093421086,"score_gpt":0.2283584799121851,"score_spread":0.224454157818764,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}