{"id":"W2084408282","doi":"10.1089/10445490050128430","title":"Cooperative Binding of TEF-1 to Repeated GGAATG-Related Consensus Elements with Restricted Spatial Separation and Orientation","year":2000,"lang":"en","type":"article","venue":"DNA and Cell Biology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Biology; Consensus sequence; Enhancer; Binding site; DNA binding site; Transcription factor; DNA; Molecular biology; Oligonucleotide; Gene; Transcription (linguistics); Genetics; Peptide sequence; Promoter; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004015867,0.0003684315,0.0004192602,0.0002312759,0.0002357516,0.0002475598,0.0003607018,0.0002716584,0.001125291],"category_scores_gemma":[0.0004964744,0.0002759153,0.0002746413,0.0001515428,0.000242954,0.0002072154,0.000487544,0.0004805777,0.0006212466],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003730578,"about_ca_system_score_gemma":0.0002452016,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007111524,"about_ca_topic_score_gemma":0.001650407,"domain_scores_codex":[0.9995698,0.00009058538,0.00001525048,0.0001470852,0.00008156025,0.00009570378],"domain_scores_gemma":[0.9997348,0.00009902117,0.00004268733,0.00003475559,0.00002279349,0.0000659744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000402596,0.00002258807,0.0002600673,0.00001889881,0.000003133991,0.00001571647,0.00001879899,0.00004418879,0.9988002,0.00004662141,0.00001957473,0.0007099336],"study_design_scores_gemma":[0.00001836735,0.0001543879,0.008287921,0.00000727773,0.000007906721,0.0002080133,0.00003706798,0.001719043,0.987999,0.0000674985,0.001485496,0.00000806993],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942189,0.0009756296,0.003929396,0.00002754655,0.000007658611,0.00002007107,0.00005456698,0.00003431907,0.0007318618],"genre_scores_gemma":[0.9954808,0.0002077928,0.002865777,0.00002495691,0.000004902291,0.00002164918,0.0002863963,0.00001333083,0.001094458],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001125291,"threshold_uncertainty_score":0.00376451,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003904322093421086,"score_gpt":0.2283584799121851,"score_spread":0.224454157818764,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}