{"id":"W2084441823","doi":"10.1038/sj.bjp.0703051","title":"Stereoselective modulatory actions of oleamide on GABA<sub>A</sub> receptors and voltage‐gated Na<sup>+</sup> channels <i>in vitro</i>: a putative endogenous ligand for depressant drug sites in CNS","year":2000,"lang":"en","type":"article","venue":"British Journal of Pharmacology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"Wellcome Trust","keywords":"Veratridine; Excitatory postsynaptic potential; Chemistry; GABAA receptor; Electrophysiology; Inhibitory postsynaptic potential; Pharmacology; Neurotransmission; Sodium channel; Biophysics; Neuroscience; Receptor; Biochemistry; Biology; Sodium","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007776899,0.0004517751,0.000207623,0.0001024735,0.00009138379,0.0002056863,0.0002199102,0.0001569879,0.0008847889],"category_scores_gemma":[0.00009203443,0.0001363753,0.0002060247,0.00007234824,0.0001732431,0.0002375945,0.0001903367,0.0002831705,0.0002458655],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002310372,"about_ca_system_score_gemma":0.000205794,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001073421,"about_ca_topic_score_gemma":0.002222119,"domain_scores_codex":[0.9999373,0.000007661093,0.000008354385,0.00001373509,0.00001131685,0.00002168066],"domain_scores_gemma":[0.9999295,0.00001113036,0.00002638379,0.000006504006,0.0000120895,0.00001441312],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001302864,0.000005318187,0.0001048702,0.00002454498,0.00000319489,0.00002832859,0.000007360167,0.00001204524,0.999239,0.00001642013,0.000006387621,0.0004221648],"study_design_scores_gemma":[0.000008158232,0.0002145471,0.002032019,0.000002830809,0.0000129005,0.000125868,0.00001564246,0.00009406214,0.9970556,0.00001070881,0.000425886,0.000001578745],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956661,0.001993784,0.0008089776,0.00003487225,0.00001588725,0.00001217509,0.0001773494,0.00002627503,0.001264417],"genre_scores_gemma":[0.9962464,0.001755369,0.0007254601,0.00004820634,0.000008684969,0.00001572033,0.000247078,0.00001120851,0.0009419483],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001073421,"threshold_uncertainty_score":0.002959967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04306255769252111,"score_gpt":0.3144421609708308,"score_spread":0.2713796032783097,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}