{"id":"W2084462172","doi":"10.1016/j.cub.2014.06.009","title":"Ancient Endo-siRNA Pathways Reveal New Tricks","year":2014,"lang":"en","type":"review","venue":"Current Biology","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Argonaute; Biology; Trans-acting siRNA; Small interfering RNA; RNA interference; RNA-induced silencing complex; Effector; Small RNA; RNA silencing; Gene silencing; Computational biology; RNA; RasiRNA; Dicer; Cell biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009561331,0.001020934,0.001263679,0.00120361,0.0003289704,0.001627487,0.001159157,0.001448633,0.002432719],"category_scores_gemma":[0.0007506394,0.0003491619,0.0003124156,0.0013792,0.001677825,0.002934293,0.0009620283,0.003175234,0.001918028],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000863656,"about_ca_system_score_gemma":0.000964798,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003884344,"about_ca_topic_score_gemma":0.0008925944,"domain_scores_codex":[0.9997973,0.00003023005,0.00002214337,0.00004354938,0.00008207598,0.00002462467],"domain_scores_gemma":[0.9996896,0.0001620479,0.00002714696,0.00001578231,0.00007021709,0.00003526181],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001077347,0.0000448378,0.0001576144,0.006493676,0.00005111499,0.0002432846,0.00007022583,0.0003885047,0.008314073,0.02596027,0.03589796,0.9222707],"study_design_scores_gemma":[0.00001082004,0.0000294138,0.0002348101,0.0006749696,0.00003826836,0.0006395222,0.00004562498,0.0001277448,0.001770262,0.007832191,0.9885797,0.00001676077],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000230446,0.994135,0.001516266,0.001228794,0.0007948866,0.000004488287,0.00002255739,0.00003219576,0.002035408],"genre_scores_gemma":[0.001746635,0.9942933,0.0007553115,0.0007839162,0.0006029436,0.000008700026,0.00004379517,0.000007127567,0.001758345],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002432719,"threshold_uncertainty_score":0.00813818,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0869194340627727,"score_gpt":0.3612960460302269,"score_spread":0.2743766119674542,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}