{"id":"W2084486694","doi":"10.1158/1538-7445.panca2012-b1","title":"Abstract B1: Validation of a panel of candidate pancreatic cancer serum biomarkers identifies SYCN and REG1B to significantly improve the performance of CA19.9.","year":2012,"lang":"en","type":"article","venue":"Diagnosis","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Mount Sinai Hospital; University of Toronto","funders":"","keywords":"Pancreatic cancer; Cancer; Medicine; CA19-9; Internal medicine; Oncology; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001116284,0.0007765908,0.0003811264,0.000759449,0.0002033795,0.0005042451,0.0002648144,0.0003364981,0.001414325],"category_scores_gemma":[0.0007560242,0.0001228894,0.0004006756,0.0004851191,0.000211464,0.0001775607,0.000282439,0.0003346833,0.0009831182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000319814,"about_ca_system_score_gemma":0.0005392997,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001107119,"about_ca_topic_score_gemma":0.0009101042,"domain_scores_codex":[0.9995951,0.00006253754,0.00003157371,0.0001128531,0.0001628328,0.00003521775],"domain_scores_gemma":[0.999705,0.00004465425,0.0000760922,0.00002474122,0.0001045718,0.00004498882],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0006452929,0.0001001009,0.01657284,0.000156719,0.00006360818,0.0001037426,0.00002630911,0.0002819208,0.9706726,0.00004292251,0.0003832963,0.01095064],"study_design_scores_gemma":[0.00005846745,0.0009281611,0.08983306,0.0000285612,0.0001184059,0.000954667,0.00003665788,0.00268276,0.9016228,0.00006099287,0.003658337,0.00001707609],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9862763,0.001851771,0.007464207,0.0001597826,0.00004008161,0.0001512363,0.002696568,0.0002344452,0.001125649],"genre_scores_gemma":[0.9679418,0.0009342234,0.02026852,0.0002239548,0.00002182184,0.0001373441,0.008356258,0.00005217989,0.002063822],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001414325,"threshold_uncertainty_score":0.005903602,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04117234139305792,"score_gpt":0.3354525561576797,"score_spread":0.2942802147646217,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}