{"id":"W2084497444","doi":"10.1210/endo.141.1.7259","title":"Intracellular Dynamics of sst5 Receptors in Transfected COS-7 Cells: Maintenance of Cell Surface Receptors during Ligand-Induced Endocytosis1","year":2000,"lang":"en","type":"article","venue":"Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Internalization; Receptor; Cell biology; Biology; Cell surface receptor; Somatostatin receptor; Intracellular; G protein-coupled receptor; Cell membrane; Transfection; Cell; Biochemistry; Biophysics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001504291,0.0002937473,0.0005203738,0.0001155185,0.00004761802,0.000006283611,0.0003534392,0.0002786205,0.0006533768],"category_scores_gemma":[0.000027965,0.0003067912,0.0002122642,0.000259737,0.0001306999,0.000008324879,0.0000555961,0.0002763639,0.00001590997],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005550624,"about_ca_system_score_gemma":0.0000708985,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000209879,"about_ca_topic_score_gemma":0.0001499917,"domain_scores_codex":[0.9978115,0.0001906361,0.0006833244,0.0005281472,0.0001551908,0.0006312109],"domain_scores_gemma":[0.9992345,0.00003512307,0.0001576321,0.0004013108,0.00008689101,0.00008454141],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003272192,0.0001742771,0.000830551,0.00008155593,0.00005067135,0.00001288762,0.0001987004,0.001594864,0.9945859,0.0001020831,0.00004115003,0.002000135],"study_design_scores_gemma":[0.00161803,0.0003998803,0.0001321218,0.00004660318,0.00002146149,0.00001685313,0.0002912469,0.0002751807,0.9960243,0.00003966353,0.0008566109,0.000278071],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975982,0.0005065796,0.0003362593,0.00004863531,0.0004415786,0.0002981133,0.00002672907,0.00002138847,0.0007224617],"genre_scores_gemma":[0.9955949,0.002070861,0.001263681,0.00001727252,0.00005395935,0.00001358493,0.00007042372,0.00004781918,0.0008674881],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002003344,"threshold_uncertainty_score":0.9999384,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006174767184352932,"score_gpt":0.2058626400139322,"score_spread":0.1996878728295793,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}