{"id":"W2084517387","doi":"10.1016/j.jconrel.2004.03.026","title":"Novel pH-sensitive supramolecular assemblies for oral delivery of poorly water soluble drugs: preparation and characterization","year":2004,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Advanced Polymer Synthesis and Characterization","field":"Chemistry","cited_by":160,"is_retracted":false,"has_abstract":false,"ca_institutions":"Micropharma (Canada); Université de Montréal","funders":"Canada Research Chairs","keywords":"Chemistry; Atom-transfer radical-polymerization; Methacrylate; Polymer chemistry; Polymer; Drug delivery; Drug carrier; Copolymer; Acrylate; Emulsion; Bioavailability; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001962084,0.0001539074,0.0005057307,0.0001004164,0.00007692306,0.00004658715,0.00006768177,0.0001030328,0.0000226035],"category_scores_gemma":[0.0001037636,0.0001131679,0.0001861432,0.00004102024,0.00003944481,0.0004804437,0.00001562896,0.00009573753,7.644871e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004435757,"about_ca_system_score_gemma":0.00009017173,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006181871,"about_ca_topic_score_gemma":0.000001115588,"domain_scores_codex":[0.9988124,0.00002472563,0.0006489237,0.0001318347,0.0002166997,0.0001654165],"domain_scores_gemma":[0.9985151,0.00008600602,0.0007046564,0.0001042008,0.0005096728,0.0000803381],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005626631,0.0001808207,0.00001590872,0.00006298073,0.0001771729,0.000004741112,0.0006179275,0.0002219434,0.9900779,0.0001176495,0.000003743166,0.002892541],"study_design_scores_gemma":[0.01275375,0.0001882724,0.0001180027,0.0001366099,0.000247559,0.00004009463,0.0001958253,0.001624082,0.9839851,0.0001236953,0.000449464,0.0001375625],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9226638,0.0001490615,0.07644583,0.0003389488,0.0001169431,0.0001733168,0.00002928618,0.000009218117,0.00007356469],"genre_scores_gemma":[0.9981633,0.0001237253,0.001127359,0.00009518342,0.0001771886,0.00001269837,0.00007141905,0.00002258009,0.0002065929],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07549942,"threshold_uncertainty_score":0.4614851,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006936820263453151,"score_gpt":0.2323481240521487,"score_spread":0.2254113037886955,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}