{"id":"W2084520414","doi":"10.1002/path.2577","title":"β1 integrin/FAK/ERK signalling pathway is essential for human fetal islet cell differentiation and survival","year":2009,"lang":"en","type":"article","venue":"The Journal of Pathology","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":118,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Diabetes Association","keywords":"Integrin; Focal adhesion; MAPK/ERK pathway; Cell biology; Islet; Biology; Kinase; Signal transduction; Cancer research; Endocrinology; Cell; Insulin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001009066,0.0001264366,0.0003419119,0.0001621179,0.0001311861,0.00002002282,0.000157987,0.000109378,0.0001376115],"category_scores_gemma":[0.0001403488,0.00008020587,0.0001381375,0.00007845175,0.00009491095,0.0000453567,0.00004512329,0.0004808523,0.000006222338],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003466529,"about_ca_system_score_gemma":0.00007311127,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003783186,"about_ca_topic_score_gemma":0.000003392265,"domain_scores_codex":[0.9986497,0.0002415823,0.0004147736,0.0001268019,0.0003185581,0.0002485754],"domain_scores_gemma":[0.9989957,0.0002028669,0.0002622873,0.0001514107,0.0002522776,0.0001355033],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005110883,0.0001645479,0.0004639089,0.00003384744,0.0000252206,0.0001687324,0.0008792033,0.000005380244,0.9933766,0.0001117254,0.0003908699,0.003868938],"study_design_scores_gemma":[0.007417066,0.007163004,0.027164,0.0001298018,0.0003928722,0.002524202,0.001156639,0.0009627565,0.9455425,0.006249637,0.001029719,0.0002678114],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9786674,0.0003785939,0.01800811,0.002198792,0.000154004,0.0002209707,0.000005313185,0.000007120322,0.0003597421],"genre_scores_gemma":[0.9978963,0.0001588078,0.0006137161,0.0003925718,0.0004390425,0.00000124461,0.000007352221,0.00001535231,0.0004756825],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04783405,"threshold_uncertainty_score":0.3270701,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02590808654876216,"score_gpt":0.3175119059936661,"score_spread":0.2916038194449039,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}