{"id":"W2084520414","doi":"10.1002/path.2577","title":"β1 integrin/FAK/ERK signalling pathway is essential for human fetal islet cell differentiation and survival","year":2009,"lang":"en","type":"article","venue":"The Journal of Pathology","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":118,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Diabetes Association","keywords":"Integrin; Focal adhesion; MAPK/ERK pathway; Cell biology; Islet; Biology; Kinase; Signal transduction; Cancer research; Endocrinology; Cell; Insulin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006303871,0.0001843193,0.0001452811,0.0001220393,0.0001482474,0.0002322214,0.00006431887,0.0001291809,0.001402912],"category_scores_gemma":[0.00008533608,0.0001018687,0.0001553447,0.00008217517,0.00007230949,0.0001162213,0.0001470328,0.0002678123,0.0003891527],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001852424,"about_ca_system_score_gemma":0.0001703861,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006279791,"about_ca_topic_score_gemma":0.00056628,"domain_scores_codex":[0.9999164,0.000009587334,0.000007534642,0.00001398471,0.00002436663,0.00002815534],"domain_scores_gemma":[0.9999508,0.000006743467,0.00001597225,0.000004509957,0.00000912969,0.00001287757],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001791901,0.00002017284,0.001042417,0.00005486273,0.000004531354,0.0001745152,0.00002714628,0.0000560064,0.9938035,0.0001051998,0.0001257323,0.004406699],"study_design_scores_gemma":[0.0000233509,0.0002514964,0.1001143,0.00003114533,0.00003386298,0.002345365,0.0001523914,0.001247647,0.8841161,0.0001471317,0.01152651,0.00001081141],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899266,0.00583358,0.001485171,0.0001527068,0.00002433357,0.00001217887,0.0004705818,0.00005163634,0.002043265],"genre_scores_gemma":[0.9939538,0.002580738,0.0009306774,0.0000384655,0.000008039418,0.00001847965,0.0006152941,0.00001043921,0.001844153],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001402912,"threshold_uncertainty_score":0.00469321,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02590808654876216,"score_gpt":0.3175119059936661,"score_spread":0.2916038194449039,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}