{"id":"W2084523295","doi":"10.1016/j.autrev.2011.10.007","title":"The biological significance of TLR3 variant, L412F, in conferring susceptibility to cutaneous candidiasis, CMV and autoimmunity","year":2011,"lang":"en","type":"review","venue":"Autoimmunity Reviews","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":78,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; SickKids Foundation; University of Toronto","funders":"","keywords":"TLR3; Autoimmunity; TLR2; Immunology; Biology; Toll-like receptor; TLR7; Innate immune system; Receptor; Immune system; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004374928,0.0007048979,0.001085432,0.0007224212,0.0001513106,0.0006568519,0.0006317463,0.0008499293,0.001471677],"category_scores_gemma":[0.0004512958,0.0001671998,0.0002563151,0.0008490535,0.0003861838,0.000654319,0.0003948915,0.00126746,0.0009824188],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003646358,"about_ca_system_score_gemma":0.0007214322,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008846046,"about_ca_topic_score_gemma":0.001371597,"domain_scores_codex":[0.9998801,0.00001824812,0.0000191496,0.0000251149,0.00004166339,0.00001568247],"domain_scores_gemma":[0.9998243,0.00007784358,0.0000307142,0.000005246784,0.00004043999,0.00002146013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002928514,0.00006118007,0.0004059802,0.008662021,0.00009660565,0.0005123947,0.00003070787,0.0003519272,0.01100286,0.002191814,0.02726589,0.9491259],"study_design_scores_gemma":[0.0000852861,0.0002000964,0.003431297,0.002343292,0.0002558531,0.004017494,0.00007677011,0.0001608124,0.002756294,0.002810642,0.9838255,0.00003657968],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000293159,0.998516,0.0001600684,0.0002226746,0.0002329752,0.00000251765,0.00002119426,0.000005792459,0.0005456723],"genre_scores_gemma":[0.001374542,0.9973119,0.0002360735,0.0001936672,0.0002847106,0.000004779059,0.00004676482,0.000001161103,0.0005463533],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001471677,"threshold_uncertainty_score":0.004923224,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09567956113437677,"score_gpt":0.3261355630337341,"score_spread":0.2304560018993573,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}