{"id":"W2084536290","doi":"10.1371/journal.pone.0110373","title":"Dextromethorphan Mediated Bitter Taste Receptor Activation in the Pulmonary Circuit Causes Vasoconstriction","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Biochemical Analysis and Sensing Techniques","field":"Nursing","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Manitoba Medical Service Foundation; Manitoba Health Research Council","keywords":"Dextromethorphan; Medicine; Pulmonary artery; Hypoxic pulmonary vasoconstriction; Pharmacology; Vascular smooth muscle; Anesthesia; Internal medicine; Smooth muscle","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001258815,0.000268271,0.0003136009,0.0001009009,0.0001655855,0.0001796119,0.0001746557,0.0003586077,0.002022551],"category_scores_gemma":[0.0001143972,0.0001514249,0.0003436432,0.0001428573,0.0002103411,0.000194148,0.0001711355,0.0004474483,0.0003157718],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002072255,"about_ca_system_score_gemma":0.0001374238,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005263707,"about_ca_topic_score_gemma":0.0008434276,"domain_scores_codex":[0.99984,0.00002430185,0.0000126053,0.00004621218,0.00003857631,0.00003822774],"domain_scores_gemma":[0.9999509,0.00001149595,0.00001178857,0.00000826331,0.000004438776,0.0000131228],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006376523,0.000003042632,0.00005094412,0.00001630161,0.000001960458,0.00003956922,0.000004193369,0.00001426543,0.9996184,0.00001759716,0.000009535145,0.0001604349],"study_design_scores_gemma":[0.00002643896,0.000361077,0.01009099,0.000005659539,0.00001839899,0.0005255323,0.00004319211,0.0008445046,0.986751,0.00003076112,0.001298285,0.000004232594],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944932,0.001149462,0.002708349,0.0001280056,0.0000224342,0.00002691442,0.0005590218,0.000049871,0.0008627929],"genre_scores_gemma":[0.9940906,0.0007984082,0.002013373,0.00007020536,0.000008613089,0.00004057181,0.0007212119,0.00001186475,0.002245102],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002022551,"threshold_uncertainty_score":0.00676614,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05066832842640996,"score_gpt":0.2383083085607115,"score_spread":0.1876399801343015,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}