{"id":"W2084545410","doi":"10.1038/nrg2317","title":"The ethics of human gene transfer","year":2008,"lang":"en","type":"review","venue":"Nature Reviews Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"U.S. Food and Drug Administration","keywords":"Biology; Context (archaeology); Gene transfer; Germline; Character (mathematics); Engineering ethics; Face (sociological concept); Field (mathematics); Genetics; Computational biology; Gene; Biotechnology; Sociology; Social science; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005211256,0.0007629429,0.001380265,0.001132052,0.001158133,0.002307174,0.001540992,0.007619003,0.004052417],"category_scores_gemma":[0.005827452,0.0003909531,0.0003486618,0.001033222,0.01206706,0.003659902,0.00249544,0.00741955,0.001493331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002997563,"about_ca_system_score_gemma":0.003046917,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001814835,"about_ca_topic_score_gemma":0.002530039,"domain_scores_codex":[0.9974232,0.001104358,0.0001196517,0.0002105638,0.0009643824,0.0001779474],"domain_scores_gemma":[0.9961689,0.002952577,0.0001453032,0.000189201,0.000394063,0.0001499672],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005072189,0.00004548034,0.0002520665,0.002085657,0.00004692274,0.0003795344,0.0003928827,0.0007536311,0.000692535,0.3612232,0.1803644,0.4537131],"study_design_scores_gemma":[0.00001294488,0.00001407587,0.0002024699,0.001399235,0.000009548842,0.0004828621,0.0001230841,0.00009354604,0.0002532972,0.1032601,0.8941342,0.00001455888],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002223109,0.9427767,0.003496795,0.03155509,0.004411658,0.000007118674,0.00002073566,0.00002445074,0.01748514],"genre_scores_gemma":[0.01379551,0.943121,0.002705299,0.02188717,0.007794453,0.00005462103,0.00004682949,0.00002867263,0.01056637],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.007619003,"threshold_uncertainty_score":0.02756006,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04266351589150989,"score_gpt":0.4205801533607986,"score_spread":0.3779166374692887,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}