{"id":"W2084557064","doi":"10.1002/cbic.200800493","title":"Heparin Antagonism by Polyvalent Display of Cationic Motifs on Virus‐Like Particles","year":2009,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Research Resources; National Cancer Institute; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research","keywords":"Capsid; Heparin; Chemistry; Biophysics; Ligand (biochemistry); Cationic polymerization; Mutant; Stereochemistry; Receptor; Biochemistry; Biology; Polymer chemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000113342,0.0001486091,0.0002530071,0.00005010311,0.00006451007,0.00001115858,0.0001257079,0.00008029957,0.0001329079],"category_scores_gemma":[0.0000401935,0.0001186194,0.0001138186,0.0001472172,0.0001145577,0.00003191354,0.00003185987,0.0001750582,0.0001073847],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005289221,"about_ca_system_score_gemma":0.00006595774,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001055171,"about_ca_topic_score_gemma":0.000003713432,"domain_scores_codex":[0.9987753,0.00001775913,0.0002541861,0.0002523605,0.0003896422,0.0003107564],"domain_scores_gemma":[0.9993174,0.00004736134,0.00006433607,0.0003031279,0.00006846725,0.0001992901],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003680888,0.0006930748,0.00294384,0.00006971623,0.00004418618,0.00001166158,0.0001397364,0.000001181973,0.9722739,0.0009825317,0.01350193,0.008970079],"study_design_scores_gemma":[0.0006185521,0.0004713066,0.02612633,0.00005631842,0.0000252062,0.00001551218,0.00002576547,0.0001611941,0.964423,0.0001949534,0.007771158,0.0001107103],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899767,0.0009061752,0.0000119565,0.003700833,0.00005407669,0.0001818569,0.0000499253,0.00003013443,0.005088349],"genre_scores_gemma":[0.9922559,0.0003137637,0.0001039092,0.0009458546,0.0001073561,0.000007756346,0.0001277375,0.00001176065,0.006125924],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02318249,"threshold_uncertainty_score":0.4837158,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0183059510641037,"score_gpt":0.3076459648508609,"score_spread":0.2893400137867572,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}