{"id":"W2084560735","doi":"10.3892/ijo.2011.1273","title":"Simvastatin inhibits cancer cell growth by inducing apoptosis correlated to activation of Bax and down-regulation of BCL-2 gene expression","year":2011,"lang":"en","type":"article","venue":"International Journal of Oncology","topic":"Cancer, Lipids, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":180,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics","keywords":"Simvastatin; Apoptosis; Cell cycle; Cancer cell; Oncogene; Cancer research; Biology; Cancer; Cell growth; Molecular medicine; Programmed cell death; Cell; Cell biology; Pharmacology; Biochemistry; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009706272,0.0002490943,0.0003103246,0.0004077675,0.0001422271,0.0001297956,0.0001186139,0.0001811839,0.001528208],"category_scores_gemma":[0.00009463636,0.00009683078,0.0003064595,0.0003212935,0.0002066145,0.0001088975,0.0001444611,0.0003780626,0.0003610828],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002014105,"about_ca_system_score_gemma":0.0002930125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005377867,"about_ca_topic_score_gemma":0.001271734,"domain_scores_codex":[0.9998713,0.00002853943,0.00001474614,0.00001538223,0.00004282846,0.00002721102],"domain_scores_gemma":[0.9999338,0.00001232865,0.00001970714,0.000008194103,0.00001545581,0.00001048137],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004207644,0.00007276153,0.0006833517,0.0001776425,0.00001957207,0.00009419598,0.00001985301,0.00005390825,0.9933304,0.0001480117,0.0001131478,0.004866474],"study_design_scores_gemma":[0.00008647437,0.001560861,0.01487975,0.00001155238,0.00003496684,0.0006302116,0.00003592375,0.0006077166,0.9753567,0.0001648326,0.006626074,0.000004830536],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9733577,0.01548025,0.005129596,0.0003290594,0.00009439738,0.0001027042,0.0004964845,0.0001551575,0.00485455],"genre_scores_gemma":[0.9871545,0.006754335,0.002129144,0.00007132618,0.00002352945,0.00005845082,0.0005199534,0.00001050846,0.003278224],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001528208,"threshold_uncertainty_score":0.00511235,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01392966961957444,"score_gpt":0.2753908033893101,"score_spread":0.2614611337697357,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}