{"id":"W2084574799","doi":"10.1111/j.1365-2567.2008.02976.x","title":"Peripheral blood CD27<sup>+</sup> IgG<sup>+</sup> B cells rapidly proliferate and differentiate into immunoglobulin‐secreting cells after exposure to low CD154 interaction","year":2008,"lang":"en","type":"article","venue":"Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Héma-Québec","funders":"Fonds Québécois de la Recherche sur la Nature et les Technologies","keywords":"CD154; CD19; CD40; CD38; Biology; B cell; Immunoglobulin G; Antibody; Naive B cell; Immunology; Molecular biology; Chemistry; Cytotoxic T cell; Cell biology; In vitro; Stem cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001143113,0.0002453648,0.0001765767,0.0001839188,0.00007913879,0.0002965816,0.00009740319,0.0001623483,0.004837332],"category_scores_gemma":[0.000115463,0.0001118717,0.0001244352,0.0001066309,0.00008942289,0.00009470966,0.00013995,0.0003813221,0.001651758],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001437628,"about_ca_system_score_gemma":0.0001417504,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005820933,"about_ca_topic_score_gemma":0.0005397754,"domain_scores_codex":[0.9998578,0.00003140271,0.00001082174,0.00002484792,0.00003268727,0.00004248896],"domain_scores_gemma":[0.9999069,0.00001918399,0.00001571842,0.00001145856,0.00001488941,0.00003176974],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002828428,0.0000252273,0.0007016541,0.00001941592,0.000003694165,0.00004593017,0.00001566143,0.00002554569,0.997198,0.00002216049,0.00006006108,0.00159995],"study_design_scores_gemma":[0.0000315747,0.0008147503,0.03455696,0.000009146883,0.00002606246,0.0006373452,0.00008290663,0.0006195735,0.9593851,0.00005271997,0.003779549,0.000004394351],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955744,0.001126324,0.001116206,0.00004467642,0.000009471443,0.00002309235,0.0003425553,0.0000414255,0.001721897],"genre_scores_gemma":[0.9903907,0.0006937008,0.001201234,0.00007703486,0.00002491009,0.00005220071,0.001485045,0.00001700129,0.006058213],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004837332,"threshold_uncertainty_score":0.01618248,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006754053923216086,"score_gpt":0.2049493732137521,"score_spread":0.198195319290536,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}