{"id":"W2084582736","doi":"10.1016/j.bmcl.2009.12.063","title":"Synthesis and antimicrobial activity of 2-fluorophenyl-4,6-disubstituted [1,3,5]triazines","year":2009,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Synthesis and Characterization of Heterocyclic Compounds","field":"Chemistry","cited_by":68,"is_retracted":false,"has_abstract":false,"ca_institutions":"Liminal BioSciences (Canada)","funders":"","keywords":"Antimicrobial; Chemistry; Bacteria; Triazine; Biological activity; Structure–activity relationship; Stereochemistry; Combinatorial chemistry; Ring (chemistry); Antibacterial agent; Antibiotics; Organic chemistry; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001065589,0.0002982296,0.0004714457,0.00003877842,0.00009686095,0.00002963947,0.0002827042,0.0001584965,0.001281548],"category_scores_gemma":[0.0002030109,0.0002807181,0.0001046612,0.0001402534,0.0002191897,0.000105381,0.00004823568,0.0001904002,0.000004899816],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006006281,"about_ca_system_score_gemma":0.00004323554,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000138904,"about_ca_topic_score_gemma":3.68828e-7,"domain_scores_codex":[0.9985601,0.00001704085,0.0003921072,0.0004212354,0.0003089475,0.0003005712],"domain_scores_gemma":[0.9989924,0.0001429472,0.0002705434,0.0003902367,0.00004765934,0.0001561951],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001129179,0.0001194331,0.0006807388,0.0002088878,0.00005220134,0.00001866303,0.0000604069,2.731239e-7,0.9899922,0.000002325457,0.0004932267,0.008258721],"study_design_scores_gemma":[0.0005049745,0.000008128674,0.005323615,0.0002265573,0.0000971386,0.00009053928,0.00002816085,0.00002233547,0.9924896,0.000004664779,0.0009356151,0.0002686902],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944185,0.0001092736,0.000113643,0.004225296,0.00007377228,0.00004320173,0.00003127109,0.00009383362,0.0008912068],"genre_scores_gemma":[0.9988396,0.00008907101,0.0001172536,0.0003775896,0.0004674315,0.000004297488,0.00002051543,0.00002236077,0.00006194492],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007990031,"threshold_uncertainty_score":0.9999645,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009375374647024658,"score_gpt":0.2118999939602154,"score_spread":0.2025246193131908,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}