{"id":"W2084626899","doi":"10.1046/j.1365-2184.2001.00192.x","title":"SERCA activity is required for timely progression through G1/S","year":2001,"lang":"en","type":"article","venue":"Cell Proliferation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Cancer Institute; Medical Research Council; Medical Research Council Canada","keywords":"SERCA; Thapsigargin; Cell biology; Endoplasmic reticulum; Intracellular; Cytosol; Cyclin; Mitosis; Cell cycle; Biology; Cyclin-dependent kinase; Chemistry; ATPase; Cell; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001426843,0.0001162463,0.0001843862,0.00003952084,0.0001334882,0.00003062566,0.00002899856,0.0001110405,0.0002798199],"category_scores_gemma":[0.00009500981,0.00009421904,0.00006918844,0.0001271329,0.00002390035,0.0002480329,0.00001038554,0.00007417434,0.0001207376],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005252359,"about_ca_system_score_gemma":0.00008391942,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004286907,"about_ca_topic_score_gemma":5.385485e-7,"domain_scores_codex":[0.9992098,0.00002806013,0.0001572738,0.0002380697,0.0001800235,0.0001868324],"domain_scores_gemma":[0.9994625,0.00004672095,0.00007692123,0.0002026332,0.0001358622,0.00007533082],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003634757,0.0009782383,0.01895702,0.0004792883,0.00005926372,0.000007382444,0.001223665,0.00001038553,0.8643774,0.0002479712,0.06069634,0.04932833],"study_design_scores_gemma":[0.003544995,0.001318753,0.003241035,0.00008873084,0.0001167885,0.00001463279,0.00004620785,0.01195092,0.9271229,0.000767479,0.0516104,0.0001771455],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9649316,0.0001618828,0.008548442,0.002369257,0.0002145092,0.00129952,0.000005246533,0.0001415108,0.022328],"genre_scores_gemma":[0.9774932,0.00004287124,0.004545986,0.001474202,0.0003868508,0.0001998354,0.00008746668,0.0000199528,0.01574961],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06274556,"threshold_uncertainty_score":0.3842141,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04075250630739712,"score_gpt":0.3196053986799221,"score_spread":0.278852892372525,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}