{"id":"W2084626899","doi":"10.1046/j.1365-2184.2001.00192.x","title":"SERCA activity is required for timely progression through G1/S","year":2001,"lang":"en","type":"article","venue":"Cell Proliferation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Cancer Institute; Medical Research Council; Medical Research Council Canada","keywords":"SERCA; Thapsigargin; Cell biology; Endoplasmic reticulum; Intracellular; Cytosol; Cyclin; Mitosis; Cell cycle; Biology; Cyclin-dependent kinase; Chemistry; ATPase; Cell; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001013321,0.0002367664,0.0002768819,0.0002105592,0.0003129973,0.0007042097,0.0001508391,0.000276146,0.001258847],"category_scores_gemma":[0.0002313551,0.0001671759,0.0002050808,0.0001251746,0.0002835233,0.0003457496,0.0001789768,0.0003249609,0.0005189449],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002973565,"about_ca_system_score_gemma":0.0003464258,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001005481,"about_ca_topic_score_gemma":0.00153945,"domain_scores_codex":[0.9999194,0.000009684782,0.000008595162,0.00002308481,0.00001676751,0.00002245736],"domain_scores_gemma":[0.9998156,0.00002677604,0.00005614246,0.00002623722,0.00002503394,0.00005025931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002539715,0.000010432,0.0005834065,0.00004588287,0.000003835539,0.00009667141,0.00001430968,0.00004516226,0.9973955,0.0001649771,0.00005760344,0.001328264],"study_design_scores_gemma":[0.00006137547,0.0002777085,0.04291343,0.0000213887,0.00002542831,0.0008023693,0.0001024375,0.00134966,0.9446592,0.0003484437,0.009427808,0.00001067277],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903427,0.004965964,0.00190163,0.0002199993,0.00007435554,0.00001935127,0.0004175743,0.0001980312,0.001860245],"genre_scores_gemma":[0.9962806,0.001388318,0.0007716847,0.00003215264,0.0000196405,0.000008589601,0.0003875118,0.00002195042,0.00108973],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001258847,"threshold_uncertainty_score":0.004211247,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04075250630739712,"score_gpt":0.3196053986799221,"score_spread":0.278852892372525,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}