{"id":"W2084649986","doi":"10.1159/000066222","title":"Transfection of p27<sup>Kip1</sup> Threonine Residue 187 Mutant Type Gene, Which Is Not Influenced by Ubiquitin-Mediated Degradation, Induces Cell Cycle Arrest in Oral Squamous Cell Carcinoma Cells","year":2002,"lang":"en","type":"article","venue":"Oncology","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"York University","keywords":"Transfection; Mutant; Cell cycle; Biology; Wild type; Molecular biology; Cyclin-dependent kinase; Cell growth; Cell culture; Ectopic expression; Mutant protein; Cell; Cell biology; Gene; Cancer research; Biochemistry; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004896562,0.0004592049,0.0009342181,0.0004726523,0.0001251256,0.00001870303,0.0002752657,0.0008993902,0.0007732516],"category_scores_gemma":[0.0002149339,0.0004789814,0.0001364842,0.001435309,0.0002132552,0.0001432144,0.00005934557,0.000915331,0.0002381283],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006817844,"about_ca_system_score_gemma":0.0006076878,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001264728,"about_ca_topic_score_gemma":0.002683765,"domain_scores_codex":[0.9964136,0.0004063099,0.001059848,0.0008092343,0.0005360664,0.0007749098],"domain_scores_gemma":[0.9979435,0.0002914743,0.0003689799,0.0006042924,0.0005026055,0.0002891248],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000668065,0.00231089,0.001591902,0.000170711,0.00003517136,0.0002319524,0.001973614,0.0007445682,0.9856238,0.00001039698,0.005523061,0.001115849],"study_design_scores_gemma":[0.01288127,0.004087303,0.004270167,0.00005731732,0.0002559024,0.00007937433,0.0001879847,0.003640815,0.9685218,0.00001751469,0.005548824,0.0004517335],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902461,0.001427519,0.0001008394,0.001001952,0.0005872492,0.001088563,0.0001748284,0.0001067879,0.005266192],"genre_scores_gemma":[0.9972153,0.0004117577,0.0005082344,0.0007220013,0.0001436713,0.00007311619,0.0002916901,0.00009938429,0.0005348913],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01710202,"threshold_uncertainty_score":0.9997662,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01443833345953589,"score_gpt":0.2451051447268879,"score_spread":0.2306668112673521,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}