{"id":"W2084649986","doi":"10.1159/000066222","title":"Transfection of p27<sup>Kip1</sup> Threonine Residue 187 Mutant Type Gene, Which Is Not Influenced by Ubiquitin-Mediated Degradation, Induces Cell Cycle Arrest in Oral Squamous Cell Carcinoma Cells","year":2002,"lang":"en","type":"article","venue":"Oncology","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"York University","keywords":"Transfection; Mutant; Cell cycle; Biology; Wild type; Molecular biology; Cyclin-dependent kinase; Cell growth; Cell culture; Ectopic expression; Mutant protein; Cell; Cell biology; Gene; Cancer research; Biochemistry; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001071488,0.0003867556,0.0002983729,0.000222158,0.000247744,0.0002165599,0.0002467115,0.0002074085,0.001814634],"category_scores_gemma":[0.00008134964,0.0001544037,0.0003259006,0.0003300879,0.0003148402,0.0001671535,0.0001474818,0.0006157644,0.0005994507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003951952,"about_ca_system_score_gemma":0.0004610206,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002461482,"about_ca_topic_score_gemma":0.003003525,"domain_scores_codex":[0.9998258,0.00001447509,0.00002478384,0.0000463334,0.00005035351,0.00003841306],"domain_scores_gemma":[0.9999089,0.0000154826,0.00002296237,0.00001871377,0.000009458638,0.00002439511],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008616482,0.00003787774,0.0001269687,0.00003242577,0.00000429785,0.00005623715,0.00001838918,0.00004265272,0.9986739,0.0001402787,0.00008901731,0.0006917653],"study_design_scores_gemma":[0.00002134559,0.0002401707,0.001890504,0.000002739954,0.00002217699,0.0001889479,0.00002890447,0.0005214402,0.9933751,0.00002198668,0.003682178,0.00000446842],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911,0.0009111377,0.003803445,0.0001311231,0.00008101443,0.00008348531,0.001214863,0.0001537655,0.002521028],"genre_scores_gemma":[0.9781988,0.00117199,0.007116577,0.00008802238,0.00002263125,0.0001806162,0.003601209,0.00008812082,0.009532055],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002461482,"threshold_uncertainty_score":0.006070554,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01443833345953589,"score_gpt":0.2451051447268879,"score_spread":0.2306668112673521,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}