{"id":"W2084663415","doi":"10.1038/sj.cdd.4402203","title":"Caspase-1 inflammasomes: choosing between death and taxis","year":2007,"lang":"en","type":"letter","venue":"Cell Death and Differentiation","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Pyroptosis; Inflammasome; Cell biology; NALP3; Caspase 1; Caspase; AIM2; Caspase 8; NLRP1; Chemistry; Programmed cell death; Innate immune system; Biology; Receptor; Apoptosis; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001129594,0.0003917191,0.0003136851,0.0001542273,0.0001807131,0.0001144138,0.0001190125,0.0009472056,0.00002023465],"category_scores_gemma":[0.00002420339,0.00037945,0.0001050264,0.00005006291,0.00005298168,0.00001087584,0.0001225863,0.0004621496,0.000008320328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000185077,"about_ca_system_score_gemma":0.00004123874,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004673926,"about_ca_topic_score_gemma":0.000009085928,"domain_scores_codex":[0.9984679,0.00006091564,0.0003243514,0.0005433941,0.0001726689,0.0004307338],"domain_scores_gemma":[0.9993081,0.00002752146,0.0001982644,0.0003138746,0.00006984582,0.00008238378],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00024257,0.0001338137,0.4391231,0.002375325,0.0008901836,0.0001489875,0.0007223007,0.000004879819,0.1656576,0.00006354225,0.3542949,0.0363428],"study_design_scores_gemma":[0.002276859,0.0004289642,0.1547247,0.0001273659,0.0004982973,0.00002173242,0.00008187831,0.000040301,0.09559934,0.0003231771,0.7444529,0.00142444],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.986707,0.004541823,0.001458927,0.00463261,0.0002211407,0.0003441644,0.0000574608,0.00002460643,0.002012207],"genre_scores_gemma":[0.9410515,0.003610971,0.0002238019,0.0374293,0.003153145,0.00003193134,0.01051964,0.0001119806,0.00386766],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.390158,"threshold_uncertainty_score":0.9998658,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01238126250107052,"score_gpt":0.2264447830443974,"score_spread":0.2140635205433269,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}