{"id":"W2084680588","doi":"10.1016/j.bcp.2004.04.030","title":"DNA methylation and breast cancer","year":2004,"lang":"en","type":"review","venue":"Biochemical Pharmacology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":228,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"Canadian Institutes of Health Research","keywords":"DNA methylation; DNA demethylation; Epigenome; Biology; Methylation; Gene silencing; Cancer research; Epigenomics; Chromatin; Cancer; Epigenetics; Genetics; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007053098,0.001247232,0.001740001,0.001693939,0.0004735022,0.001119063,0.001446588,0.001541258,0.002995508],"category_scores_gemma":[0.0005574466,0.0004243691,0.0003490351,0.002282317,0.001155525,0.001304645,0.0008547144,0.002897288,0.002833501],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001164705,"about_ca_system_score_gemma":0.001151636,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001572853,"about_ca_topic_score_gemma":0.003958222,"domain_scores_codex":[0.9998232,0.00003387624,0.00001622482,0.00003329409,0.00007194666,0.00002147419],"domain_scores_gemma":[0.9998466,0.0000475637,0.00001958257,0.00001004112,0.00005372974,0.00002253383],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001438446,0.00009781639,0.0001627903,0.004447457,0.00006846827,0.0003574159,0.00005022165,0.0005320709,0.006296756,0.008091604,0.08655766,0.893194],"study_design_scores_gemma":[0.00002272093,0.00003961764,0.0003797986,0.0005040396,0.00004447667,0.0008926395,0.00003217806,0.00008514113,0.001202674,0.003542856,0.9932417,0.00001212556],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000936287,0.9966555,0.0004164573,0.0006499966,0.0007527253,0.000004432979,0.00001217583,0.00001255588,0.001402549],"genre_scores_gemma":[0.001014174,0.9942933,0.0004152619,0.0004965228,0.0008135925,0.00001073221,0.00002858685,0.000002372755,0.002925456],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002995508,"threshold_uncertainty_score":0.01002103,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02710037226196546,"score_gpt":0.3731477919329796,"score_spread":0.3460474196710142,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}