{"id":"W2084738456","doi":"10.1016/j.vetpar.2007.12.001","title":"P-glycoprotein selection in strains of Haemonchus contortus resistant to benzimidazoles","year":2007,"lang":"en","type":"article","venue":"Veterinary Parasitology","topic":"Helminth infection and control","field":"Veterinary","cited_by":80,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds Québécois de la Recherche sur la Nature et les Technologies","keywords":"Haemonchus contortus; Biology; Gene; Anthelmintic; Locus (genetics); Allele; P-glycoprotein; Genetics; Glycoprotein; Drug resistance; Nematode; Multiple drug resistance","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001161722,0.0003016994,0.0002549357,0.0004085109,0.0002661458,0.0002749418,0.0002245897,0.0003658982,0.001236373],"category_scores_gemma":[0.0004313068,0.000187216,0.0002586818,0.0002666591,0.000313136,0.0001995742,0.0002422192,0.0004410361,0.0001680439],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002414668,"about_ca_system_score_gemma":0.0001390491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003267196,"about_ca_topic_score_gemma":0.003434058,"domain_scores_codex":[0.9998217,0.00004559679,0.00001288167,0.0000258857,0.00003372743,0.00006019236],"domain_scores_gemma":[0.9998325,0.00004204514,0.00003428422,0.0000135695,0.00002874392,0.00004879122],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001010157,0.0002188268,0.004383017,0.00001307755,0.00001740878,0.0004372924,0.0001631248,0.0000568157,0.9920988,0.00008394656,0.00006387614,0.001453655],"study_design_scores_gemma":[0.0003721263,0.01304411,0.4970044,0.00002499643,0.0001770753,0.008690229,0.001770137,0.003478317,0.4724604,0.0002219084,0.002694265,0.00006197577],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9997244,0.00001894611,0.00003484593,0.00001315299,0.000001793322,0.000005694397,0.00003244252,0.000002015956,0.0001665982],"genre_scores_gemma":[0.9990579,0.00004107506,0.0001241227,0.00002198244,0.000004059568,0.000008481153,0.0001264817,0.000005948554,0.0006099225],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003267196,"threshold_uncertainty_score":0.00649637,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06128374601433143,"score_gpt":0.3909034731105183,"score_spread":0.3296197270961868,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}