{"id":"W2084746053","doi":"10.1002/(sici)1097-0215(20000201)85:3<424::aid-ijc20>3.0.co;2-s","title":"Long-term inhibitory effect of the orally active and pure antiestrogen EM-800 on the growth of human breast cancer xenografts in nude mice","year":2000,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier universitaire de Québec; Université Laval","funders":"","keywords":"Antiestrogen; Medicine; Cancer; Inhibitory postsynaptic potential; Breast cancer; Tamoxifen; Internal medicine; Oncology; Orally active; Mammary gland; Cancer research; Endocrinology; Oral administration","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009680032,0.0002431638,0.0002089915,0.0001542121,0.00006112648,0.0001069303,0.0001679963,0.0001760773,0.0007668779],"category_scores_gemma":[0.00007208222,0.00008825291,0.000130657,0.00009877713,0.0001013384,0.0001015979,0.00009104908,0.0002565303,0.0002493169],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001190315,"about_ca_system_score_gemma":0.0000974175,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004069502,"about_ca_topic_score_gemma":0.001187052,"domain_scores_codex":[0.9999411,0.00001341574,0.000003922843,0.000008638179,0.00001750935,0.00001538846],"domain_scores_gemma":[0.9999412,0.00001222751,0.00001355188,0.000006733352,0.000008221656,0.00001802559],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005510897,0.0001291823,0.0002828701,0.00002411269,0.000009366669,0.00002622212,0.00001140406,0.00007283763,0.9957282,0.0000229878,0.00003598108,0.003105663],"study_design_scores_gemma":[0.00005149762,0.006357824,0.01060463,0.000008204888,0.00004891816,0.0002164753,0.00002645291,0.0004593523,0.9789295,0.0000202089,0.003271957,0.000005135757],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996931,0.001643885,0.0002620925,0.00001939461,0.000009909189,0.0000082046,0.0001584069,0.00002358408,0.0009436515],"genre_scores_gemma":[0.9941862,0.00153007,0.0006223964,0.00002814205,0.00001220307,0.00001994377,0.0006400981,0.00001116757,0.002949786],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007668779,"threshold_uncertainty_score":0.002565444,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003159991690865882,"score_gpt":0.2657203472629207,"score_spread":0.2625603555720548,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}