{"id":"W2084746444","doi":"10.1074/jbc.m309268200","title":"Identification and Functional Characterization of Voltage-dependent Calcium Channels in T Lymphocytes","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":107,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"NFAT; Jurkat cells; Calcium channel; Molecular biology; T cell; Nifedipine; T lymphocyte; Voltage-dependent calcium channel; CD8; Bay K8644; Biology; Cell biology; Chemistry; Endocrinology; Internal medicine; Calcium; Antigen; Immunology; Immune system; Medicine; Calcineurin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003378084,0.0000798492,0.0001305457,0.0000343194,0.00002251176,0.00001048615,0.00004464397,0.0001739174,0.00006103605],"category_scores_gemma":[0.0002126369,0.00006413389,0.00005460209,0.00006923474,0.00005535456,0.000008032332,0.00001636157,0.00006674315,6.942648e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002254423,"about_ca_system_score_gemma":0.0000434776,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":4.997423e-7,"about_ca_topic_score_gemma":9.257575e-8,"domain_scores_codex":[0.999263,0.00003746958,0.0003788022,0.0001292309,0.000107571,0.00008392039],"domain_scores_gemma":[0.9994182,0.00001155988,0.0002978663,0.00006883584,0.0001565367,0.00004702715],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001216939,0.00006586666,0.005839126,0.00001644429,0.00001191953,0.000001165664,0.0000108379,0.00009890527,0.9934434,0.00002870677,0.00002632854,0.0003355618],"study_design_scores_gemma":[0.0005732565,0.00008455521,0.01924345,0.00001265309,0.000005019155,0.0000818552,0.00005955974,0.00008606986,0.9785187,0.0001032188,0.001162625,0.00006899506],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906006,0.0001911564,0.008749138,0.00004052795,0.0002669398,0.00004242464,0.000005242322,0.000002000927,0.0001019928],"genre_scores_gemma":[0.9991298,0.0001841905,0.0000255412,0.00003163696,0.0002379602,0.000002565032,0.00004975327,0.000004407031,0.0003341292],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0149247,"threshold_uncertainty_score":0.2615304,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02332033982147634,"score_gpt":0.2434078396890837,"score_spread":0.2200874998676074,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}