{"id":"W2084746444","doi":"10.1074/jbc.m309268200","title":"Identification and Functional Characterization of Voltage-dependent Calcium Channels in T Lymphocytes","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":107,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"NFAT; Jurkat cells; Calcium channel; Molecular biology; T cell; Nifedipine; T lymphocyte; Voltage-dependent calcium channel; CD8; Bay K8644; Biology; Cell biology; Chemistry; Endocrinology; Internal medicine; Calcium; Antigen; Immunology; Immune system; Medicine; Calcineurin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001077829,0.0002314356,0.0002467127,0.0004406438,0.0001805897,0.0004427938,0.0002619642,0.0003650389,0.0008924115],"category_scores_gemma":[0.0002106019,0.00008154576,0.0003209527,0.0003334908,0.0001520185,0.0002944385,0.0001405899,0.0004609237,0.0004654406],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001502174,"about_ca_system_score_gemma":0.0001518545,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003164565,"about_ca_topic_score_gemma":0.0002557056,"domain_scores_codex":[0.9998796,0.00001183537,0.00001442837,0.0000292039,0.00002891662,0.00003600736],"domain_scores_gemma":[0.9999059,0.00001837634,0.00002088414,0.00001083046,0.00001622644,0.00002771278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000358455,0.000009955217,0.000121707,0.00001885951,0.000001021243,0.000036725,0.000008369242,0.00001082531,0.9990415,0.00002525772,0.000007110631,0.0006827182],"study_design_scores_gemma":[0.0000635363,0.0007121003,0.03475661,0.00002327343,0.0000650558,0.002467029,0.0001852258,0.001312371,0.9504426,0.0003271337,0.009628044,0.00001705008],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9824771,0.005317361,0.008557409,0.0002406246,0.00005349597,0.0001143028,0.001169876,0.0000938991,0.001975768],"genre_scores_gemma":[0.9828803,0.003614064,0.008223321,0.0001870316,0.0001098238,0.0001257277,0.002566854,0.00003012626,0.002262831],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008924115,"threshold_uncertainty_score":0.002985358,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02332033982147634,"score_gpt":0.2434078396890837,"score_spread":0.2200874998676074,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}