{"id":"W2084808179","doi":"10.1016/j.devcel.2007.02.011","title":"aPKC Controls Microtubule Organization to Balance Adherens Junction Symmetry and Planar Polarity during Development","year":2007,"lang":"en","type":"article","venue":"Developmental Cell","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":118,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; U.S. Department of Energy","keywords":"Adherens junction; Biology; Cell biology; Microtubule; Gastrulation; Centrosome; Polarity (international relations); Morphogenesis; Cytoskeleton; Dynein; Cell polarity; Cilium; Astral microtubules; Embryo; Cadherin; Embryogenesis; Cell; Genetics; Cell cycle","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002717201,0.0005231705,0.0003524917,0.0008215494,0.0008389034,0.002138054,0.001040585,0.0007680096,0.001644844],"category_scores_gemma":[0.0005760119,0.0006307257,0.0001958896,0.0004294403,0.0005926269,0.001623711,0.001060474,0.00140985,0.0008524794],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002051855,"about_ca_system_score_gemma":0.0006318289,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001587851,"about_ca_topic_score_gemma":0.003656907,"domain_scores_codex":[0.9995891,0.00003848529,0.00003667084,0.0001018554,0.0001259694,0.0001079142],"domain_scores_gemma":[0.9993021,0.00005538515,0.0001537884,0.0000849377,0.0001620625,0.0002417171],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003035558,0.00001927691,0.001182579,0.00006894293,0.000009751387,0.0002199724,0.0000583079,0.000334932,0.9888269,0.002268765,0.0001856959,0.006521364],"study_design_scores_gemma":[0.00006189152,0.00009823129,0.02982668,0.00003654143,0.00003985607,0.0005678136,0.0002258873,0.009038499,0.9512392,0.001523817,0.007311604,0.00002997391],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9798064,0.00364993,0.009621453,0.0003115089,0.0001000833,0.00002187524,0.0002390963,0.0002321916,0.006017375],"genre_scores_gemma":[0.9915212,0.0008142829,0.002162801,0.0000697682,0.00002122682,0.00002386082,0.0001661478,0.00009192977,0.005128626],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002138054,"threshold_uncertainty_score":0.01488733,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003783987145293413,"score_gpt":0.1925388215025844,"score_spread":0.188754834357291,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}