{"id":"W2084811906","doi":"10.1038/onc.2014.37","title":"The WIP1 oncogene promotes progression and invasion of aggressive medulloblastoma variants","year":2014,"lang":"en","type":"article","venue":"Oncogene","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Cancer Institute","keywords":"Medulloblastoma; Biology; Cancer research; CXCR4; Gene knockdown; Oncogene; Protein kinase B; Metastasis; Cell; Cell cycle; Cell culture; Signal transduction; Cell biology; Receptor; Cancer; Biochemistry; Genetics; Chemokine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004546025,0.0001626936,0.000184845,0.00002511528,0.0002244746,0.00001768086,0.0001856984,0.0001216496,0.000002820367],"category_scores_gemma":[0.0007847695,0.000106458,0.00005436601,0.00007854638,0.0002330733,0.000002773332,0.0002535631,0.00006136687,0.000004328733],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000905095,"about_ca_system_score_gemma":0.00006158047,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005732369,"about_ca_topic_score_gemma":0.00004278207,"domain_scores_codex":[0.9988883,0.0001391867,0.0002367347,0.0003196297,0.0001862154,0.0002299178],"domain_scores_gemma":[0.9990176,0.00006588361,0.0003487203,0.0003470265,0.0001429411,0.0000778032],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008236662,0.00004588618,0.001137546,0.00002440232,0.00006011959,0.000003305425,0.00007707396,0.000003490159,0.9210714,0.00005649495,0.0003067589,0.07713114],"study_design_scores_gemma":[0.000501183,0.0008101424,0.001327053,0.0001116199,0.00002649264,0.00003066101,0.00004917632,0.00007547089,0.9810466,0.0001517903,0.01572509,0.0001447654],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932238,0.005023835,0.0003725249,0.0002524809,0.0001418603,0.0002365726,0.00001062512,0.0000121334,0.0007261788],"genre_scores_gemma":[0.9975701,0.0007337768,0.001156291,0.00005889458,0.0002132441,0.00003184692,0.0000182444,0.00002307618,0.0001945103],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07698637,"threshold_uncertainty_score":0.4341232,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008940095024311126,"score_gpt":0.2595661761409298,"score_spread":0.2506260811166187,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}