{"id":"W2084871159","doi":"10.1054/ghir.2000.0167","title":"Unexpected and unexplained phenotypes in transgenic models","year":2000,"lang":"en","type":"letter","venue":"Growth Hormone & IGF Research","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Phenotype; Transgene; Biology; Genetically modified mouse; Genetics; Computational biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.00143556,0.001107739,0.001932523,0.003451113,0.0003762543,0.0001964161,0.0007849203,0.002578164,0.0003110289],"category_scores_gemma":[0.0002831794,0.001013862,0.0004140716,0.002945067,0.0008494219,0.0005207187,0.0002349511,0.01002397,0.000315094],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000552074,"about_ca_system_score_gemma":0.0009691652,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001821556,"about_ca_topic_score_gemma":0.0000642932,"domain_scores_codex":[0.9901895,0.000837556,0.001396921,0.001954049,0.002829624,0.002792333],"domain_scores_gemma":[0.9965876,0.0006210356,0.0001511556,0.001315556,0.0006926763,0.0006319894],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002664452,0.000473196,0.0007425578,0.001095352,0.0004861511,0.003931134,0.002807848,0.00000492524,0.004718754,0.000397302,0.9773691,0.005309202],"study_design_scores_gemma":[0.03422569,0.01002934,0.04176733,0.002539299,0.001201695,0.0009617746,0.001351234,0.003685307,0.004241101,0.03927561,0.8539987,0.006722973],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.48828,0.03001067,0.00006428643,0.4305727,0.0002486884,0.004606385,0.0002621902,0.0005486765,0.04540644],"genre_scores_gemma":[0.879258,0.02123693,0.000448276,0.08354784,0.003675944,0.0007153741,0.002008157,0.0006405451,0.00846891],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3909781,"threshold_uncertainty_score":0.9992312,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07797399606916477,"score_gpt":0.3219883511254389,"score_spread":0.2440143550562741,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}