{"id":"W2084886678","doi":"10.1097/01.tp.0000136965.22023.60","title":"Induction of Xenogeneic Neonatal Tolerance to Transgenic Human Leukocyte Antigen Class I Grafts","year":2004,"lang":"en","type":"article","venue":"Transplantation","topic":"Xenotransplantation and immune response","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"HIV Legal Network; Hospital for Sick Children","funders":"","keywords":"Major histocompatibility complex; Xenotransplantation; Immunology; Human leukocyte antigen; Immune tolerance; Immune system; Biology; Transgene; Antigen; Histocompatibility; Humanized mouse; Genetically modified mouse; Miniature swine; MHC class I; Transplantation; Immunologic Tolerance; Genetics; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000376396,0.0003934231,0.0002300553,0.0002066535,0.00009519625,0.0001817673,0.0003608495,0.0002312594,0.001485578],"category_scores_gemma":[0.0002017803,0.00009561849,0.0002069646,0.000104024,0.0002154318,0.0001676708,0.0002390057,0.000569353,0.0003581391],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001628385,"about_ca_system_score_gemma":0.0002017617,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001200168,"about_ca_topic_score_gemma":0.0001884705,"domain_scores_codex":[0.9998081,0.00003371619,0.00002714767,0.00003676815,0.00005383815,0.00004034415],"domain_scores_gemma":[0.9997324,0.00006144082,0.0000749417,0.00003870743,0.00002658578,0.00006582429],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001343548,0.00009340209,0.0002883662,0.00006574453,0.000004697647,0.00009928691,0.00004021962,0.00005239818,0.9977435,0.0001158137,0.00002933301,0.001332936],"study_design_scores_gemma":[0.00001909559,0.001693027,0.002574224,0.00001798838,0.00001766818,0.0004057087,0.00003722678,0.0003734067,0.9938559,0.00004104827,0.00096184,0.000002898784],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947692,0.0006371842,0.002813254,0.0000213513,0.00002928844,0.00006448587,0.0001504997,0.00006790946,0.001446856],"genre_scores_gemma":[0.9931561,0.0007788211,0.00256363,0.00007798099,0.00001672408,0.000111222,0.0005632281,0.00003900078,0.00269319],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001485578,"threshold_uncertainty_score":0.004969776,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02126313143776475,"score_gpt":0.2972406542472819,"score_spread":0.2759775228095172,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}