{"id":"W2084937852","doi":"10.1002/glia.10127","title":"p16<sup><i>ink4a</i></sup> and retinoic acid modulate rhoA and GFAP expression during induction of a stellate phenotype in U343 MG‐A astrocytoma cells","year":2002,"lang":"en","type":"article","venue":"Glia","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"RHOA; Biology; Glial fibrillary acidic protein; Vimentin; Molecular biology; Cancer research; Western blot; Cell biology; Signal transduction; Immunology; Biochemistry; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001226577,0.0002064824,0.0003517984,0.0002085633,0.0000560856,0.0000153299,0.00005516153,0.0002111434,0.0001140539],"category_scores_gemma":[0.0000342844,0.0002031289,0.00004723368,0.0002403045,0.00008769254,0.0001098022,0.00009329779,0.000353252,0.00001708312],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008423398,"about_ca_system_score_gemma":0.0000181804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004682762,"about_ca_topic_score_gemma":0.000008080327,"domain_scores_codex":[0.9986228,0.00005986672,0.0003541561,0.0004121521,0.0002489382,0.0003020675],"domain_scores_gemma":[0.9993283,0.00001441216,0.0001335009,0.0003264997,0.00005196636,0.0001453929],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003534385,0.00006599928,0.001527897,0.0002298586,0.00002497367,0.00008183828,0.001443078,0.0004129208,0.9897687,0.000004131564,0.0001409916,0.005946168],"study_design_scores_gemma":[0.004622912,0.0003767075,0.01330215,0.0007938725,0.00007471774,0.0001375027,0.0001804452,0.006676494,0.9731796,0.00004279889,0.0003854612,0.000227331],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962676,0.002341594,0.0000444738,0.00009762789,0.0001091253,0.0003819506,0.000008855939,0.00005314961,0.0006956796],"genre_scores_gemma":[0.9983371,0.0004414755,0.0007802041,0.00003530592,0.00009016844,0.00000922558,0.000006359672,0.00003901276,0.0002611717],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01658909,"threshold_uncertainty_score":0.8283356,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01106039132111509,"score_gpt":0.2071037929093881,"score_spread":0.196043401588273,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}