{"id":"W2084976312","doi":"10.3389/fnagi.2014.00313","title":"Amyloid Beta1–42 and the Phoshorylated Tau Threonine 231 in Brains of Aged Cynomolgus Monkeys (Macaca fascicularis)","year":2014,"lang":"en","type":"article","venue":"Frontiers in Aging Neuroscience","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Senile plaques; Cerebral amyloid angiopathy; Tauopathy; Pathological; Pathology; Amyloid (mycology); Dementia; Alzheimer's disease; Immunohistochemistry; Angiopathy; Psychology; Medicine; Disease; Neuroscience; Neurodegeneration; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006158943,0.0001774888,0.0004045465,0.0003052914,0.0001236266,0.00003609986,0.0002657498,0.00005123849,0.00000574778],"category_scores_gemma":[0.0004501499,0.0001224365,0.00006972375,0.0007982529,0.001008272,0.0001533346,0.0001258076,0.0003479173,0.000001662225],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006023792,"about_ca_system_score_gemma":0.0001010683,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003695854,"about_ca_topic_score_gemma":0.00002469752,"domain_scores_codex":[0.9980096,0.0002453927,0.0002958055,0.0004692638,0.0005043292,0.0004756467],"domain_scores_gemma":[0.9991951,0.00009024631,0.00009095361,0.0003886199,0.00003445001,0.0002006468],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005468988,0.0004428957,0.9782525,0.00007499498,0.0001438452,0.0003456407,0.001206626,0.0001435497,0.004071484,0.0001789687,0.0006501872,0.01394245],"study_design_scores_gemma":[0.007091964,0.0001996903,0.9631888,0.0001576585,0.00009203873,0.00002763885,0.000148335,0.02476216,0.003348094,0.0006444713,0.0001792229,0.0001599803],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928342,0.002883207,0.001122107,0.001430042,0.0002771365,0.0006600106,0.000008088859,0.00003202748,0.0007531738],"genre_scores_gemma":[0.9984536,0.0003722196,0.0005506341,0.0004599722,0.00002252033,0.00002715698,0.000005604484,0.00001585514,0.00009247112],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02461861,"threshold_uncertainty_score":0.4992815,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01435743219763323,"score_gpt":0.2724627222252809,"score_spread":0.2581052900276476,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}