{"id":"W2085055023","doi":"10.1139/o04-057","title":"Induction of G<sub>1</sub> cell cycle arrest in human umbilical vein endothelial cells by flavone's inhibition of the extracellular signal regulated kinase cascade","year":2004,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Bioactive natural compounds","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Umbilical vein; Angiogenesis; Kinase; Cell biology; Cell cycle; Biology; Human umbilical vein endothelial cell; MAPK/ERK pathway; Extracellular; Endothelial stem cell; Cyclin-dependent kinase 1; Chemistry; Biochemistry; Cancer research; Cell; In vitro","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006622628,0.0002821785,0.0001607897,0.0001852478,0.0001167082,0.0001449226,0.00009108832,0.0001234885,0.001365081],"category_scores_gemma":[0.00009626173,0.00007867701,0.0001676612,0.0001036613,0.0001269968,0.0001296768,0.00007802326,0.000283174,0.0003128526],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002847416,"about_ca_system_score_gemma":0.0001507355,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007932546,"about_ca_topic_score_gemma":0.001202539,"domain_scores_codex":[0.999961,0.000009304403,0.000003671635,0.000007022494,0.000006919069,0.00001205021],"domain_scores_gemma":[0.9999615,0.0000122489,0.000009137871,0.000006821546,0.000005107757,0.000005119686],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009138654,0.00003014474,0.0001349352,0.00003106345,0.000004290144,0.00003800791,0.000008826983,0.00005730572,0.9976034,0.0001602522,0.0000635138,0.001776974],"study_design_scores_gemma":[0.00002801397,0.0003386935,0.004120868,0.000003799068,0.000006840422,0.0001315626,0.000007974454,0.0005173504,0.9926251,0.00007116853,0.002146424,0.000002121104],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98831,0.004232461,0.003580698,0.0001206207,0.00004769819,0.00007125782,0.0005191244,0.0001118808,0.003006191],"genre_scores_gemma":[0.9916335,0.001970063,0.003310609,0.00006705364,0.000017547,0.00006890271,0.0006373249,0.00001616473,0.002278863],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001365081,"threshold_uncertainty_score":0.004566669,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00472020147374214,"score_gpt":0.2051255676383208,"score_spread":0.2004053661645787,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}