{"id":"W2085105837","doi":"10.1016/j.ymthe.2004.03.009","title":"Novel mouse model for carcinoembryonic antigen-based therapy","year":2004,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":80,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"National Cancer Institute","keywords":"Carcinoembryonic antigen; Humanized mouse; Genetic enhancement; Biology; Transgene; Cancer research; Gene; Immunology; Cancer; Medicine; Genetics; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001758333,0.0002552579,0.0003290499,0.0001333834,0.0001375807,0.00002922156,0.0001990286,0.0001221382,0.00005020801],"category_scores_gemma":[0.00001529516,0.0001960828,0.0003625771,0.0001607904,0.0001061275,0.00003602679,0.00001668791,0.0001991068,0.00002839345],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000722185,"about_ca_system_score_gemma":0.0004433552,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000154682,"about_ca_topic_score_gemma":0.000006108422,"domain_scores_codex":[0.9984087,0.000019657,0.0002271987,0.0003813374,0.0004516112,0.0005114928],"domain_scores_gemma":[0.9991001,0.00003394494,0.0000471053,0.0004249377,0.0001864765,0.000207424],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002052547,0.0006385929,0.0005385011,0.00003332565,0.0001529548,0.00002690274,0.00017189,0.006857144,0.9816353,0.0017209,0.00008922801,0.006082697],"study_design_scores_gemma":[0.01298354,0.001102061,0.001614136,0.00003425416,0.0000113711,0.00001984064,0.0000144917,0.03462678,0.9385168,0.00110703,0.009653899,0.0003157759],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.837529,0.002557663,0.1545598,0.003948658,0.00004163518,0.0009669159,0.00005433661,0.00007034667,0.0002716189],"genre_scores_gemma":[0.9719706,0.001140119,0.0157888,0.008105258,0.0001053514,0.0001508896,0.0001138473,0.0000871151,0.002537979],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.138771,"threshold_uncertainty_score":0.7996026,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06344041079047481,"score_gpt":0.3353616109084351,"score_spread":0.2719212001179603,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}