{"id":"W2085105837","doi":"10.1016/j.ymthe.2004.03.009","title":"Novel mouse model for carcinoembryonic antigen-based therapy","year":2004,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":80,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"National Cancer Institute","keywords":"Carcinoembryonic antigen; Humanized mouse; Genetic enhancement; Biology; Transgene; Cancer research; Gene; Immunology; Cancer; Medicine; Genetics; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001083522,0.001645815,0.0007631821,0.002946607,0.0007043946,0.001044056,0.001228853,0.001783924,0.004635549],"category_scores_gemma":[0.0003489878,0.0005096598,0.0009661641,0.0006436166,0.0008710801,0.00134692,0.0004917156,0.003567642,0.001459304],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001000655,"about_ca_system_score_gemma":0.0005471738,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009676121,"about_ca_topic_score_gemma":0.001454192,"domain_scores_codex":[0.9992484,0.0001413765,0.00007435406,0.0001861955,0.000204671,0.0001449964],"domain_scores_gemma":[0.999512,0.0001048994,0.0001073533,0.00009803018,0.00005281629,0.0001249577],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007455542,0.000571091,0.0003217363,0.0001215344,0.00004574747,0.0003336107,0.00004976394,0.0002688757,0.9881824,0.004553383,0.001218446,0.003587897],"study_design_scores_gemma":[0.0002524125,0.002067897,0.001298888,0.00005783235,0.0001720861,0.001934608,0.0000552185,0.002955904,0.9646668,0.001374141,0.02513062,0.00003346324],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8166141,0.01683482,0.1249163,0.004088285,0.002394132,0.001400693,0.007868932,0.003057584,0.02282505],"genre_scores_gemma":[0.8877542,0.009632601,0.04309818,0.0009469052,0.0003665369,0.001671392,0.006997792,0.000445772,0.04908665],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004635549,"threshold_uncertainty_score":0.01550746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06344041079047481,"score_gpt":0.3353616109084351,"score_spread":0.2719212001179603,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}