{"id":"W2085135889","doi":"10.1186/1471-2121-11-99","title":"3D nuclear organization of telomeres in the Hodgkin cell lines U-HO1 and U-HO1-PTPN1: PTPN1 expression prevents the formation of very short telomeres including \"t-stumps\"","year":2010,"lang":"en","type":"article","venue":"BMC Cell Biology","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Telomere; Biology; Telomerase; Cell biology; Cell culture; Molecular biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006491581,0.00022753,0.0004329425,0.0002286985,0.0001527771,0.00001561318,0.0003317524,0.0002705873,0.00008882],"category_scores_gemma":[0.0003353787,0.0001343218,0.00006279119,0.0004752926,0.0003200964,0.0001551028,0.0001891017,0.0003620139,0.000007875884],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001895749,"about_ca_system_score_gemma":0.00007321694,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001283069,"about_ca_topic_score_gemma":0.0001140694,"domain_scores_codex":[0.99827,0.000261497,0.0006535424,0.0003076484,0.0002221553,0.0002851596],"domain_scores_gemma":[0.9985401,0.0004629988,0.0003083379,0.0004734627,0.0001558216,0.00005925934],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001153804,0.0002128668,0.1661639,0.0003456693,0.000007238694,0.000001859826,0.002633229,0.000007348707,0.8265513,0.00006043591,0.0001862948,0.003714484],"study_design_scores_gemma":[0.001241744,0.0003786147,0.1765979,0.0001857452,0.00008937182,0.00003717621,0.003721718,0.0005925742,0.8138236,0.0001105917,0.002976847,0.0002441358],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976447,0.000475471,0.0001451705,0.0001256229,0.0002323369,0.0006276675,0.00001517524,0.00003052089,0.0007033118],"genre_scores_gemma":[0.9974982,0.0007172985,0.001335451,0.0001387456,0.0001429131,0.00001289925,0.00007096855,0.00002934829,0.00005415408],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01272775,"threshold_uncertainty_score":0.5477484,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02300606162287935,"score_gpt":0.2699690994463159,"score_spread":0.2469630378234365,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}