{"id":"W2085179320","doi":"10.1016/j.bpj.2014.01.009","title":"Star Light, Star Bright, First Molecule I See Tonight","year":2014,"lang":"en","type":"letter","venue":"Biophysical Journal","topic":"Advanced Fluorescence Microscopy Techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Total internal reflection fluorescence microscope; Fluorophore; Microscopy; Optics; Prism; Numerical aperture; Computer science; Physics; Nanotechnology; Fluorescence; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003425383,0.0005340854,0.000359986,0.0002540852,0.001775422,0.001567414,0.0006102412,0.006297766,0.03311455],"category_scores_gemma":[0.001758543,0.0003809985,0.0004963166,0.0001646454,0.001022285,0.0009622983,0.0003938261,0.008459935,0.01607242],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001573815,"about_ca_system_score_gemma":0.0006534396,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001746741,"about_ca_topic_score_gemma":0.002937747,"domain_scores_codex":[0.9997631,0.0000309989,0.00001109516,0.00005101042,0.00008827135,0.00005550124],"domain_scores_gemma":[0.9995998,0.0001715925,0.00002188278,0.00003628322,0.00005745908,0.0001130799],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003653584,0.00006268799,0.0003630967,0.00007373664,0.0000128734,0.002483348,0.00003494744,0.0000797801,0.005200201,0.0087768,0.9628231,0.01972419],"study_design_scores_gemma":[0.0000893766,0.0001163162,0.0006311308,0.00004715933,0.0000124819,0.001881601,0.00006302389,0.0005077592,0.005901183,0.009451465,0.9812723,0.00002633578],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.005767925,0.006475312,0.005514742,0.7889513,0.05139962,0.0001840856,0.0004813896,0.001050241,0.1401753],"genre_scores_gemma":[0.06264458,0.006513709,0.006337557,0.3500887,0.01623506,0.0001950781,0.0003673762,0.0003291453,0.5572888],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.03311455,"threshold_uncertainty_score":0.1107792,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007093852824014562,"score_gpt":0.2499814777116262,"score_spread":0.2428876248876116,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}