{"id":"W2085179320","doi":"10.1016/j.bpj.2014.01.009","title":"Star Light, Star Bright, First Molecule I See Tonight","year":2014,"lang":"en","type":"letter","venue":"Biophysical Journal","topic":"Advanced Fluorescence Microscopy Techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Total internal reflection fluorescence microscope; Fluorophore; Microscopy; Optics; Prism; Numerical aperture; Computer science; Physics; Nanotechnology; Fluorescence; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0001460171,0.0006948916,0.0006137822,0.0001181109,0.000332248,0.000186213,0.001042583,0.00123258,0.0001055404],"category_scores_gemma":[0.0000534789,0.00059075,0.00054534,0.0001244071,0.0002498521,0.0000132175,0.0002779536,0.002328962,0.0001549255],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001194866,"about_ca_system_score_gemma":0.0001665499,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007156662,"about_ca_topic_score_gemma":0.000002624772,"domain_scores_codex":[0.9970105,0.0001602143,0.0005623962,0.0008292858,0.0005462102,0.0008913633],"domain_scores_gemma":[0.9981717,0.000024046,0.0004409415,0.000871708,0.0002583554,0.0002332762],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003079249,0.00003829592,0.000003948071,0.00003240881,0.0000652137,0.000299809,0.000007134372,7.327296e-7,0.4896393,0.000008967339,0.5097976,0.00007590108],"study_design_scores_gemma":[0.0001910526,0.0003416825,0.00001043876,0.00008067285,0.00003934195,0.0002283412,0.000001561614,0.00001214372,0.4275618,0.00009893597,0.5709798,0.0004542384],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.06294535,0.002130921,0.1142516,0.8091734,0.003629613,0.00214405,0.0006477511,0.0005751161,0.00450215],"genre_scores_gemma":[0.01638958,0.002179942,0.06797533,0.8250341,0.07380789,0.0001324171,0.002057959,0.0009530638,0.01146975],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.07017828,"threshold_uncertainty_score":0.9999727,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007093852824014562,"score_gpt":0.2499814777116262,"score_spread":0.2428876248876116,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}