{"id":"W2085198161","doi":"10.1039/c2an35420a","title":"Scanning positional variations in single-nucleotide polymorphism of DNA: an electrochemical study","year":2012,"lang":"en","type":"article","venue":"The Analyst","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; University of Toronto","keywords":"Dielectric spectroscopy; Scanning electrochemical microscopy; Oligonucleotide; Nucleotide; DNA; Chemistry; Electrochemistry; Single-nucleotide polymorphism; Analytical Chemistry (journal); Crystallography; Materials science; Electrode; Biochemistry; Gene; Genotype; Chromatography","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004036629,0.0002658212,0.000277939,0.0002504268,0.0001294431,0.0002694018,0.0004191821,0.0005836269,0.0004284919],"category_scores_gemma":[0.0007207714,0.0002217506,0.0001569216,0.0004129042,0.0002646092,0.000311252,0.0001711108,0.0004873142,0.0001534929],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001733513,"about_ca_system_score_gemma":0.0001285865,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004494236,"about_ca_topic_score_gemma":0.0006246,"domain_scores_codex":[0.9996986,0.00006454538,0.00002323454,0.00008181274,0.0001043091,0.00002756572],"domain_scores_gemma":[0.9996883,0.0001175369,0.00005856084,0.00002578251,0.00006939465,0.00004058449],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002783317,0.00001810527,0.0005776488,0.00003404187,0.000008389709,0.00003816517,0.00002368125,0.0001220192,0.9976935,0.0000425022,0.000007093036,0.001406913],"study_design_scores_gemma":[0.000007341383,0.0004817353,0.007214086,0.000007988818,0.00002805226,0.0004811349,0.00007765846,0.003982739,0.9868259,0.00007694647,0.0008043253,0.00001229576],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9879187,0.002642493,0.008704435,0.00009973071,0.00001999791,0.00002626355,0.00007644825,0.00002507233,0.0004868965],"genre_scores_gemma":[0.9883898,0.001324734,0.009705925,0.00004926098,0.00001066677,0.00001637288,0.00006039404,0.000004558631,0.0004382334],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005836269,"threshold_uncertainty_score":0.0021348,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01376026573005756,"score_gpt":0.2795944208041259,"score_spread":0.2658341550740683,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}