{"id":"W2085216261","doi":"10.1016/s0003-2697(02)00634-6","title":"A quantitative diffraction-based sandwich immunoassay","year":2003,"lang":"en","type":"article","venue":"Analytical Biochemistry","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Axela (Canada)","funders":"","keywords":"Detection limit; Immunoassay; Antibody; Chemistry; Primary and secondary antibodies; Diffraction; Chromatography; Conjugated system; Biology; Immunology; Optics; Physics; Polymer; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004835154,0.002465625,0.002745821,0.003536187,0.0009271901,0.001964587,0.004378805,0.003091403,0.003558035],"category_scores_gemma":[0.003813019,0.001908986,0.001424383,0.001496007,0.001344142,0.001363577,0.002160731,0.004342283,0.005285201],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001282211,"about_ca_system_score_gemma":0.001381879,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007165922,"about_ca_topic_score_gemma":0.001290188,"domain_scores_codex":[0.9910433,0.002469995,0.0005941665,0.001909908,0.00345277,0.0005298569],"domain_scores_gemma":[0.9963732,0.001555327,0.0002213231,0.0005086915,0.0009687037,0.0003727358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003157427,0.0002615932,0.000847201,0.0002746751,0.00009361192,0.00005386498,0.00006254123,0.0002484514,0.9690661,0.0009219155,0.001810064,0.0260443],"study_design_scores_gemma":[0.0002132106,0.0008715494,0.002578984,0.00005450272,0.0001968612,0.001130389,0.0000696921,0.01948491,0.9642243,0.001120675,0.009934003,0.0001208778],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.04151292,0.003940145,0.9404268,0.0008183615,0.0008148403,0.0009001878,0.001024646,0.005309837,0.005252237],"genre_scores_gemma":[0.09526598,0.00176091,0.8869442,0.00075817,0.0003683489,0.00130818,0.002126649,0.0002440666,0.01122352],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.004835154,"threshold_uncertainty_score":0.02557105,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03076501717437798,"score_gpt":0.3507895575883104,"score_spread":0.3200245404139325,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}