{"id":"W2085238801","doi":"10.1016/j.jmb.2008.10.072","title":"Crystal Structure of Diaminopimelate Epimerase from Arabidopsis thaliana, an Amino Acid Racemase Critical for l-Lysine Biosynthesis","year":2008,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":45,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Stereochemistry; Amino acid; Biochemistry; Cysteine; Biosynthesis; Active site; Amidohydrolase; Arabidopsis thaliana; Chemistry; Enzyme; Isomerase; Lysine; Biology; Mutant; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001591688,0.0004442497,0.000446198,0.0002004788,0.000522978,0.0006571806,0.0005878331,0.0004926665,0.002063328],"category_scores_gemma":[0.0003761641,0.0002291486,0.0001575675,0.0003451895,0.0002055038,0.0003796825,0.0001242611,0.001122437,0.0002936138],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001458356,"about_ca_system_score_gemma":0.001093763,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01349248,"about_ca_topic_score_gemma":0.01886836,"domain_scores_codex":[0.9999479,0.000004280836,0.000002125618,0.00001248802,0.00002220417,0.00001102847],"domain_scores_gemma":[0.9998228,0.00005250347,0.00003385498,0.000006322636,0.00003344604,0.00005103439],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002888148,0.001015887,0.01789951,0.001223949,0.0002685646,0.007814754,0.001202559,0.01164947,0.8581795,0.00966184,0.04820884,0.03998715],"study_design_scores_gemma":[0.003048745,0.001558017,0.1660142,0.0002704582,0.0008053059,0.008406827,0.00430219,0.1885841,0.4756427,0.007094442,0.1439107,0.0003622771],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9788124,0.004038579,0.002868607,0.002084542,0.000230846,0.0000405037,0.00420509,0.0004914528,0.00722811],"genre_scores_gemma":[0.9752792,0.002984597,0.004614263,0.0004843733,0.00004695519,0.00004686916,0.01088828,0.00009929112,0.005556156],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01349248,"threshold_uncertainty_score":0.02682787,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01416211729019922,"score_gpt":0.2744139650432246,"score_spread":0.2602518477530254,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}