{"id":"W2085241378","doi":"10.1016/s0006-3495(01)75905-x","title":"Gating Charge Immobilization Caused by the Transition between Inactivated States in the Kv1.5 Channel","year":2001,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Gating; Shaker; Conductance; Repolarization; Chemistry; Depolarization; Biophysics; Analytical Chemistry (journal); Electrophysiology; Physics; Chromatography","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001284591,0.0001545164,0.000128352,0.00008036625,0.0001949094,0.0004112406,0.0003026414,0.0002739169,0.001367418],"category_scores_gemma":[0.0003289695,0.0001419913,0.0001598414,0.00008286039,0.0004453054,0.0003693931,0.000274294,0.0004647104,0.0001729788],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002852168,"about_ca_system_score_gemma":0.0001276387,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006079198,"about_ca_topic_score_gemma":0.0005841472,"domain_scores_codex":[0.9999284,0.00001019112,0.000003983838,0.00001348936,0.00001398149,0.00003005552],"domain_scores_gemma":[0.9998919,0.00003498808,0.00002606722,0.00001375235,0.00001052693,0.00002273413],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007108919,0.00004900555,0.0004921563,0.00004058771,0.000012282,0.0002190346,0.0000876622,0.0003560975,0.994435,0.0008866302,0.0001439174,0.002566697],"study_design_scores_gemma":[0.00009290344,0.000228748,0.009290326,0.00001310583,0.00003607234,0.0003018817,0.00008367041,0.005669812,0.9830376,0.0004234211,0.0007979395,0.00002437192],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989262,0.0001246202,0.000521954,0.00006252681,0.00001250892,0.000002090131,0.00001837349,0.00001278473,0.0003189529],"genre_scores_gemma":[0.9994375,0.00006016957,0.0001134875,0.00002335774,0.000003826352,0.000001691614,0.00002831982,0.000004969608,0.0003267165],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001367418,"threshold_uncertainty_score":0.004574478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01598096774006085,"score_gpt":0.250913680269477,"score_spread":0.2349327125294162,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}