{"id":"W2085273309","doi":"10.1016/j.pupt.2007.11.003","title":"Phosphodiesterase 4 inhibitors delay human eosinophil and neutrophil apoptosis in the absence and presence of salbutamol","year":2007,"lang":"en","type":"article","venue":"Pulmonary Pharmacology & Therapeutics","topic":"Phosphodiesterase function and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Tays; Tampereen Tuberkuloosisäätiö; Fondation pour la Recherche Médicale","keywords":"Rolipram; Eosinophil; Apoptosis; Phosphodiesterase 3; Zaprinast; Phosphodiesterase; Pharmacology; Medicine; Immunology; Endocrinology; Internal medicine; Chemistry; Asthma; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002725033,0.0002829806,0.0004724802,0.0001623437,0.0001785094,0.0003902458,0.0003029093,0.0003402919,0.002395696],"category_scores_gemma":[0.000426189,0.0002293037,0.0002516557,0.0001212021,0.0003219426,0.000297571,0.0002025703,0.001094518,0.0004044871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002700862,"about_ca_system_score_gemma":0.0005110019,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000994035,"about_ca_topic_score_gemma":0.002300575,"domain_scores_codex":[0.9997641,0.00005718135,0.00002055321,0.00001816671,0.00004463012,0.00009544646],"domain_scores_gemma":[0.99976,0.0000955149,0.00003547538,0.00003249939,0.00001947398,0.00005708685],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01286629,0.0006130391,0.0005668031,0.0000652019,0.00003014496,0.000162758,0.00005513754,0.0001938241,0.9788042,0.0002388068,0.0003043325,0.006099681],"study_design_scores_gemma":[0.0007564938,0.006192337,0.007433115,0.00001282098,0.0000572499,0.0002705567,0.0001110484,0.001241419,0.9822016,0.0001014095,0.001613759,0.000008212013],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967192,0.001548979,0.0004158699,0.0001971587,0.0001140663,0.00002430584,0.0001349466,0.00002901542,0.0008163439],"genre_scores_gemma":[0.9964377,0.0008202324,0.0003048991,0.00007288354,0.00002963793,0.00002812951,0.0003033347,0.000006955415,0.001996239],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002395696,"threshold_uncertainty_score":0.008014381,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01544301110176884,"score_gpt":0.2871709640217711,"score_spread":0.2717279529200023,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}