{"id":"W2085316849","doi":"10.1002/stem.447","title":"Decoded Calreticulin-Deficient Embryonic Stem Cell Transcriptome Resolves Latent Cardiophenotype","year":2010,"lang":"en","type":"article","venue":"Stem Cells","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; Ted Nash Long Life Foundation; J. Willard and Alice S. Marriott Foundation; American Heart Association","keywords":"Calreticulin; Biology; Transcriptome; Induced pluripotent stem cell; Stem cell; Embryonic stem cell; Cell biology; Computational biology; Genetics; Gene; Endoplasmic reticulum; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009312622,0.0001507753,0.0001785959,0.0002198976,0.00009677179,0.0002538556,0.00008144566,0.0001299382,0.0007160553],"category_scores_gemma":[0.0001598799,0.00008055623,0.0001063191,0.0001511457,0.0001271895,0.0001242679,0.000167211,0.0002471596,0.0002000406],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001777334,"about_ca_system_score_gemma":0.0001342442,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002779313,"about_ca_topic_score_gemma":0.0007541544,"domain_scores_codex":[0.9999285,0.000007926905,0.000005466417,0.00002725179,0.0000201712,0.00001073552],"domain_scores_gemma":[0.9999025,0.00002042872,0.00002830075,0.00001548572,0.00001679376,0.000016531],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004090786,0.000002002462,0.001064505,0.000009050995,0.000002786918,0.00002778454,0.00001421371,0.00007593592,0.9976879,0.00004684004,0.00001419179,0.001013925],"study_design_scores_gemma":[0.000008775665,0.0001533893,0.1287743,0.000009040809,0.00005764167,0.0004242109,0.0001488852,0.006042873,0.8615642,0.000383375,0.002424049,0.000009408058],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899244,0.0002988973,0.007659929,0.00004297704,0.00000928446,0.0000120257,0.001300152,0.0001025921,0.0006497956],"genre_scores_gemma":[0.9915308,0.0002599137,0.004044519,0.00005010816,0.000003489485,0.00002064363,0.002771332,0.00003683496,0.001282352],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007160553,"threshold_uncertainty_score":0.002395451,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006634493160173841,"score_gpt":0.2095942809128206,"score_spread":0.2029597877526468,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}