{"id":"W2085343346","doi":"10.1007/s00424-005-1493-4","title":"Modest intracellular acidification suppresses death signaling in ouabain-treated cells","year":2005,"lang":"en","type":"article","venue":"Pflügers Archiv - European Journal of Physiology","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hôtel-Dieu de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research; Kidney Foundation of Canada","keywords":"Ouabain; Cycloheximide; Intracellular; Programmed cell death; Cell biology; Chemistry; Cell culture; Intracellular pH; Biology; Biochemistry; Molecular biology; Sodium; Protein biosynthesis; Apoptosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003469292,0.0001532368,0.0001978687,0.0001238422,0.00004648706,0.00001156824,0.0002333935,0.00004557675,0.00002601322],"category_scores_gemma":[0.0000164626,0.0001374305,0.0001211008,0.00007064923,0.00006602958,0.00001377264,0.00002599304,0.0001739494,0.00001489996],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000143093,"about_ca_system_score_gemma":0.00003317565,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002708527,"about_ca_topic_score_gemma":0.000002842476,"domain_scores_codex":[0.9986767,0.0003130343,0.0004708359,0.000211243,0.00009918908,0.0002289529],"domain_scores_gemma":[0.9993734,0.00001754231,0.0002702899,0.0001719424,0.0000855336,0.00008130394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002464939,0.0001024536,0.0003118177,0.0000131032,0.00003281423,0.00001937302,0.0002317285,0.02551272,0.9711035,0.00003243914,0.0001287676,0.002264754],"study_design_scores_gemma":[0.000753737,0.0003081578,0.01280453,0.00003137654,0.00002305207,0.00002431776,0.00007876613,0.0007308816,0.9798529,0.00009302906,0.005139442,0.000159837],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952348,0.0003457497,0.003503484,0.0001461723,0.00009770119,0.00007435192,0.000005898042,0.000005914983,0.0005859422],"genre_scores_gemma":[0.9976547,0.0003020281,0.001158532,0.00007044603,0.0005952648,9.317322e-7,0.0001061345,0.00002944376,0.00008248966],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02478184,"threshold_uncertainty_score":0.5604254,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01134838701382585,"score_gpt":0.2138979649789423,"score_spread":0.2025495779651164,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}