{"id":"W2085362274","doi":"10.4161/cc.5.13.2899","title":"&amp;gamma;H2AX as a Checkpoint Maintenance Signal","year":2006,"lang":"en","type":"article","venue":"Cell Cycle","topic":"Fault Detection and Control Systems","field":"Engineering","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Biology; G2-M DNA damage checkpoint; CHEK1; Cell biology; DNA damage; Cell cycle checkpoint; Genetics; Cancer; Cell cycle; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00007679721,0.000119412,0.0001287964,0.00003983346,0.00004727408,0.00004189955,0.00009126404,0.00006525009,0.0003370053],"category_scores_gemma":[0.000003965662,0.0001169476,0.00007964822,0.0001002372,0.00001617529,0.00005399977,0.000009838507,0.0001141932,0.00216775],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006482009,"about_ca_system_score_gemma":0.000008138772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003242681,"about_ca_topic_score_gemma":0.00013336,"domain_scores_codex":[0.9992912,0.00001353248,0.0001901418,0.0001360005,0.0001147952,0.0002543069],"domain_scores_gemma":[0.9997097,0.00001431792,0.00002303341,0.0001747038,0.00001840185,0.00005986787],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004101349,0.0001016382,0.0002764091,0.000181488,0.00003697944,0.0000508358,0.0003256088,0.1213475,0.8280665,0.000724868,0.0414986,0.007348572],"study_design_scores_gemma":[0.00118607,0.00003748779,0.000957794,0.00003391256,0.00001283661,0.00004464842,0.00008792536,0.09635594,0.07820269,0.001251024,0.8214004,0.0004292869],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.69907,0.0005573591,0.00877046,0.00006676729,0.0006252397,0.0001731431,0.000004675536,0.0006593522,0.290073],"genre_scores_gemma":[0.9855705,0.000005886575,0.0001156082,0.00004749406,0.0002703256,0.00002769505,0.000004237163,0.00002973808,0.01392854],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7799018,"threshold_uncertainty_score":0.9986092,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003966430297352375,"score_gpt":0.1804129230911161,"score_spread":0.1764464927937637,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}