{"id":"W2085430830","doi":"10.1517/13543784.11.12.1795","title":"Novel therapies for sepsis: antiendotoxin therapies","year":2002,"lang":"en","type":"review","venue":"Expert Opinion on Investigational Drugs","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Health Sciences Centre; Manitoba Health","funders":"","keywords":"Sepsis; Lipopolysaccharide; Immune system; Lipid A; Monoclonal antibody; Immunology; Receptor; Septic shock; Biology; Antibody; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003760321,0.0006128828,0.001111127,0.0004246805,0.0004465531,0.00006115008,0.0004429081,0.0007280853,0.0005691799],"category_scores_gemma":[0.0002002,0.0004817537,0.0006438779,0.0002313598,0.0003669132,0.000193821,0.00005410481,0.0004255876,0.0009652823],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001254854,"about_ca_system_score_gemma":0.0002796746,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001315892,"about_ca_topic_score_gemma":2.069776e-7,"domain_scores_codex":[0.9976003,0.0003972384,0.0008788738,0.0005734632,0.000130991,0.0004191614],"domain_scores_gemma":[0.9977437,0.001076236,0.0005524321,0.0004507977,0.0001390659,0.00003782222],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008951822,0.0002190606,3.77326e-7,0.001051255,0.001083329,2.77137e-7,0.003350179,0.000001972948,0.002651657,0.03211194,0.09308983,0.8663506],"study_design_scores_gemma":[0.0008699226,0.0001678948,0.00000330539,0.004099541,0.00002543301,0.00002640555,0.000178659,0.000005251959,0.00127835,0.0003886604,0.9924306,0.0005259367],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000008298737,0.9938639,0.0002087808,0.001110869,0.002540842,0.001342857,0.0002007547,0.0001411104,0.0005826156],"genre_scores_gemma":[0.00001319494,0.9893602,0.0007059816,0.0007918718,0.0004491704,0.001436496,0.003572836,0.0000890833,0.003581162],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8993408,"threshold_uncertainty_score":0.9998126,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08159723834029357,"score_gpt":0.3380841695788234,"score_spread":0.2564869312385298,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}