{"id":"W2085475144","doi":"10.1210/en.2010-0137","title":"OASIS/CREB3L1 Induces Expression of Genes Involved in Extracellular Matrix Production But Not Classical Endoplasmic Reticulum Stress Response Genes in Pancreatic β-Cells","year":2010,"lang":"en","type":"article","venue":"Endocrinology","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research; University of Toronto; National Institutes of Health; Vanderbilt University; National Institute of Diabetes and Digestive and Kidney Diseases; Banting and Best Diabetes Centre, University of Toronto; Heart and Stroke Foundation of Canada; Juvenile Diabetes Research Foundation International","keywords":"Endoplasmic reticulum; Extracellular matrix; Internal medicine; Endocrinology; Gene; Unfolded protein response; Extracellular; Gene expression; Biology; Cell biology; Chemistry; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001364474,0.0003798246,0.0002608665,0.000225558,0.0001162141,0.0003258307,0.0001834965,0.0001729295,0.002272239],"category_scores_gemma":[0.0001123521,0.0001481893,0.0003393063,0.0001872519,0.000307238,0.0001780853,0.0002255118,0.0008528669,0.0005385897],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003753148,"about_ca_system_score_gemma":0.0003440325,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007538149,"about_ca_topic_score_gemma":0.001110724,"domain_scores_codex":[0.999832,0.00001185394,0.0000156179,0.00003920823,0.00004900491,0.00005224612],"domain_scores_gemma":[0.9998566,0.00001594146,0.00004075354,0.00001462868,0.00001716052,0.00005491807],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006785721,0.00001543769,0.00005781501,0.00002044965,0.000002092856,0.00001771265,0.000005116119,0.00001225656,0.9994496,0.00002609762,0.00002158219,0.0003040184],"study_design_scores_gemma":[0.00002517042,0.0002115674,0.00539297,0.00000670449,0.00001052101,0.0001055706,0.0000450976,0.0005552756,0.991607,0.00004011038,0.001995584,0.000004441857],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923472,0.0008702488,0.003096561,0.0001513022,0.00009342316,0.00004117197,0.001452756,0.0001695126,0.00177777],"genre_scores_gemma":[0.9870495,0.0006898819,0.002383915,0.0001812903,0.00002574798,0.00006614683,0.003340666,0.00009335708,0.006169547],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002272239,"threshold_uncertainty_score":0.00760144,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01045777468037555,"score_gpt":0.2546521345290371,"score_spread":0.2441943598486616,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}