{"id":"W2085498425","doi":"10.1074/jbc.m603307200","title":"Secretion of Vascular Endothelial Growth Factor by Primary Human Fibroblasts at Senescence","year":2006,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":582,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"National Institute on Aging","keywords":"Senescence; Carcinogenesis; Biology; Angiogenesis; Cell biology; Cancer cell; Neoplastic transformation; Malignant transformation; Cancer research; Immunology; Cancer; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001683429,0.0001871059,0.0005262339,0.00003198904,0.00005819862,0.000008015159,0.000169219,0.0002549096,0.0003983198],"category_scores_gemma":[0.0001874106,0.0001271713,0.0003033434,0.0001001813,0.000216421,0.0000540321,0.00005226672,0.0002989502,0.000003592516],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001426884,"about_ca_system_score_gemma":0.00006081275,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000177087,"about_ca_topic_score_gemma":3.971045e-7,"domain_scores_codex":[0.9984816,0.00004004187,0.0006453313,0.0002029506,0.0003935491,0.0002365456],"domain_scores_gemma":[0.9988688,0.0001216276,0.0004782314,0.0001614249,0.0002085877,0.0001613001],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002314536,0.0002300584,0.06637681,0.0002088957,0.00003571915,0.00005590301,0.00001349819,7.518903e-7,0.9313636,0.000004224558,0.001286117,0.0001929129],"study_design_scores_gemma":[0.00110405,0.0003216648,0.1128196,0.0001628968,0.00003526495,0.0002928913,0.0000173329,0.00000272906,0.8832309,0.00007133488,0.001809391,0.0001319976],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978664,0.0008793427,0.0001408811,0.0001282002,0.00005010909,0.00007184682,0.00004913819,0.00001940135,0.0007947077],"genre_scores_gemma":[0.9983729,0.0002711625,0.0003257696,0.00009666954,0.0004604335,0.000001016752,0.00006912772,0.00001076031,0.00039216],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04813278,"threshold_uncertainty_score":0.5185896,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01339943175525795,"score_gpt":0.2342339899988359,"score_spread":0.220834558243578,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}