{"id":"W2085498425","doi":"10.1074/jbc.m603307200","title":"Secretion of Vascular Endothelial Growth Factor by Primary Human Fibroblasts at Senescence","year":2006,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":582,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"National Institute on Aging","keywords":"Senescence; Carcinogenesis; Biology; Angiogenesis; Cell biology; Cancer cell; Neoplastic transformation; Malignant transformation; Cancer research; Immunology; Cancer; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003526561,0.0003824151,0.0002812677,0.0001855517,0.0001323005,0.0003092805,0.0001543144,0.0002483371,0.001876486],"category_scores_gemma":[0.0003376519,0.0001399076,0.0003492309,0.0001679214,0.0001100254,0.0001234812,0.0001883979,0.0004494283,0.001134716],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001892612,"about_ca_system_score_gemma":0.0002162814,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006382062,"about_ca_topic_score_gemma":0.000632083,"domain_scores_codex":[0.999797,0.00004569901,0.0000252896,0.00003520498,0.00005360624,0.00004312031],"domain_scores_gemma":[0.9998178,0.00004947696,0.00002186052,0.00004526198,0.0000354097,0.00003033958],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001749931,0.00003759674,0.0002522868,0.00005308131,0.000006901456,0.00007128478,0.00003034953,0.0000598775,0.995704,0.00007951005,0.0002431581,0.003286967],"study_design_scores_gemma":[0.0000918368,0.00145405,0.004659652,0.00002598367,0.0000385555,0.0008065492,0.00002799422,0.0008340551,0.9761072,0.0001245695,0.01581934,0.00001027732],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9433325,0.01898655,0.02275474,0.0004745402,0.00052734,0.0003015237,0.002904861,0.0005098527,0.01020809],"genre_scores_gemma":[0.9699947,0.006330098,0.01128946,0.0002526641,0.0001353719,0.0001605231,0.004164092,0.00004779981,0.007625299],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001876486,"threshold_uncertainty_score":0.006277442,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01339943175525795,"score_gpt":0.2342339899988359,"score_spread":0.220834558243578,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}