{"id":"W2085516936","doi":"10.1902/jop.2003.74.8.1219","title":"Effect of Hydroxamic Acid‐Based Matrix Metalloproteinase Inhibitors on Human Gingival Cells and <i>Porphyromonas gingivalis</i>","year":2003,"lang":"en","type":"article","venue":"Journal of Periodontology","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Ono Pharmaceutical","keywords":"Porphyromonas gingivalis; Matrix metalloproteinase; Chemistry; Viability assay; Matrix metalloproteinase inhibitor; Cell growth; Periodontitis; Hydroxamic acid; HaCaT; Cytotoxicity; Zymography; Fibroblast; Keratinocyte; Cell; Pharmacology; Molecular biology; Microbiology; Biochemistry; In vitro; Biology; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003696844,0.000802191,0.0004945985,0.0002844694,0.0002018261,0.0002913587,0.0002170478,0.0003107571,0.001747689],"category_scores_gemma":[0.0002715453,0.0001573144,0.000341455,0.0002580094,0.0002008712,0.0001460158,0.0002005673,0.0004287325,0.000515488],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002076765,"about_ca_system_score_gemma":0.0003159766,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001899973,"about_ca_topic_score_gemma":0.001555617,"domain_scores_codex":[0.9996736,0.0001006281,0.00003293946,0.00004228598,0.0000708184,0.00007982787],"domain_scores_gemma":[0.9997519,0.00009444719,0.00005646125,0.00002277449,0.00004058344,0.00003374611],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003556914,0.000499997,0.001237504,0.000596544,0.00005208737,0.0002633794,0.0001266524,0.0002648398,0.9818859,0.00007908159,0.0003415626,0.01109541],"study_design_scores_gemma":[0.0002117761,0.006977037,0.009333604,0.00005482324,0.0001046345,0.0006225442,0.0001179802,0.0006674438,0.9755051,0.00004002173,0.006350568,0.00001446704],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9743984,0.02096953,0.0008357098,0.0001464275,0.0001042001,0.00009266913,0.0005417029,0.00003333364,0.002878064],"genre_scores_gemma":[0.9845451,0.009701032,0.002132799,0.0001115999,0.00006749155,0.0001365994,0.00155115,0.00001293165,0.001741396],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001899973,"threshold_uncertainty_score":0.00584662,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007130905474355763,"score_gpt":0.2690742012042667,"score_spread":0.261943295729911,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}