{"id":"W2085516936","doi":"10.1902/jop.2003.74.8.1219","title":"Effect of Hydroxamic Acid‐Based Matrix Metalloproteinase Inhibitors on Human Gingival Cells and <i>Porphyromonas gingivalis</i>","year":2003,"lang":"en","type":"article","venue":"Journal of Periodontology","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Ono Pharmaceutical","keywords":"Porphyromonas gingivalis; Matrix metalloproteinase; Chemistry; Viability assay; Matrix metalloproteinase inhibitor; Cell growth; Periodontitis; Hydroxamic acid; HaCaT; Cytotoxicity; Zymography; Fibroblast; Keratinocyte; Cell; Pharmacology; Molecular biology; Microbiology; Biochemistry; In vitro; Biology; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008821095,0.0002509184,0.0005136017,0.0001601261,0.00008741103,0.00001676459,0.0001666398,0.0002382473,0.00003182429],"category_scores_gemma":[0.0001573641,0.0002033518,0.0002734846,0.00007542758,0.0001419317,0.00001019665,0.00003621269,0.0002296086,0.000002317326],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002169524,"about_ca_system_score_gemma":0.00009412144,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001095272,"about_ca_topic_score_gemma":0.000004393175,"domain_scores_codex":[0.9982704,0.0004671657,0.0005245808,0.0002527009,0.0002155674,0.0002695952],"domain_scores_gemma":[0.9989583,0.00003250796,0.0005084975,0.000257641,0.0001015991,0.0001414164],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003572431,0.0000902894,0.0003303056,0.00007081871,0.00008985038,0.00007428981,0.00002513158,0.00002808952,0.9980854,0.000265956,0.0002568182,0.0003258125],"study_design_scores_gemma":[0.001854092,0.007645166,0.00003225145,0.00005417358,0.0001085389,0.0001805324,0.00001710028,0.00001280833,0.9868892,0.0001320998,0.002895307,0.0001786897],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967239,0.001843403,0.0004284008,0.00006215178,0.0003670789,0.0002223574,0.000008440416,0.000005224383,0.0003390537],"genre_scores_gemma":[0.9986139,0.00003570957,0.0008912508,0.0001284835,0.0001964937,0.000007196016,0.000005408313,0.00002778688,0.00009376387],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01119615,"threshold_uncertainty_score":0.8292444,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007130905474355763,"score_gpt":0.2690742012042667,"score_spread":0.261943295729911,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}