{"id":"W2085525271","doi":"10.1016/j.tcb.2011.06.008","title":"Taking a “good” look at free radicals in the aging process","year":2011,"lang":"en","type":"review","venue":"Trends in Cell Biology","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":586,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Reactive oxygen species; Oxidative stress; Biology; Free-radical theory of aging; Mitochondrial ROS; Caenorhabditis elegans; Phenotype; Cell biology; Oxidative damage; Mitochondrion; Accelerated aging; Radical; Biochemistry; Chemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007215202,0.0005632929,0.001063259,0.0003462665,0.00008045464,0.00002173554,0.001635252,0.0009857407,0.00024942],"category_scores_gemma":[0.00007187128,0.0004059306,0.0003207331,0.0003205344,0.0002690553,0.000002480537,0.0004968179,0.0005929001,0.00003695743],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005964427,"about_ca_system_score_gemma":0.0001280082,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001166723,"about_ca_topic_score_gemma":0.0008666154,"domain_scores_codex":[0.9969206,0.0006038923,0.0007410637,0.0009357397,0.0001054906,0.0006931777],"domain_scores_gemma":[0.998191,0.00007176163,0.000487881,0.00115267,0.00002506561,0.00007162158],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002267966,0.0003378429,0.001513508,0.003253833,0.0001123137,0.0000556652,0.001826788,0.00001647311,0.0006558758,0.0001589631,0.001266396,0.9907796],"study_design_scores_gemma":[0.0005138996,0.0002059734,0.00008315991,0.0004678285,0.0001537537,0.00006440045,0.00005360116,0.000005644445,0.0005790645,0.0002634475,0.9970113,0.0005979468],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00244464,0.9834641,0.00005940879,0.00004005959,0.0003023603,0.000326056,0.00005094463,0.00001495752,0.01329749],"genre_scores_gemma":[0.02275296,0.9745196,0.0002190998,0.0002562754,0.0003804446,0.0001483885,0.0006657288,0.0000747844,0.0009827884],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9957449,"threshold_uncertainty_score":0.9998392,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05333254166232682,"score_gpt":0.3369176607739347,"score_spread":0.2835851191116079,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}