{"id":"W2085534091","doi":"10.1093/nar/gki1003","title":"Synthesis and hybridization studies of oligonucleotides containing 1-(2-deoxy-2- -C-hydroxymethyl- -D-ribofuranosyl)thymine (2'- -hm-dT)","year":2005,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Fonds Québécois de la Recherche sur la Nature et les Technologies; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"RNA; Oligonucleotide; Phosphoramidite; DNA; Biology; Thymine; Nucleotide; RNase H; Molecular biology; Nucleic acid thermodynamics; Stereochemistry; Biochemistry; Chemistry; RNase P; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002537615,0.0004496719,0.0002558551,0.0001372554,0.0001983818,0.0002077004,0.0002026455,0.0004484836,0.0008469917],"category_scores_gemma":[0.000458148,0.0002443269,0.0002996935,0.0001255933,0.00023698,0.0002065373,0.0001496512,0.0003686652,0.0004420046],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001824426,"about_ca_system_score_gemma":0.0002063377,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003645022,"about_ca_topic_score_gemma":0.0006601266,"domain_scores_codex":[0.9997935,0.00006120853,0.00001357147,0.00007242578,0.00003293282,0.00002638372],"domain_scores_gemma":[0.9997107,0.0001073697,0.00007511833,0.00002419369,0.00003729113,0.00004527383],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001858301,0.000009334414,0.00008980693,0.00003538546,0.000003891348,0.00002383344,0.00003704077,0.00008399972,0.9985,0.00003126251,0.000005900812,0.001160955],"study_design_scores_gemma":[0.000003449883,0.0003451557,0.001069524,0.000003562603,0.0000150374,0.0001821369,0.00002225305,0.0003382715,0.9969978,0.00001998906,0.0009966673,0.000006069765],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9764153,0.001931187,0.01931138,0.00006577377,0.00003357048,0.00007806301,0.0001327234,0.0001509755,0.001881082],"genre_scores_gemma":[0.954226,0.00143461,0.04122466,0.000135808,0.0000209584,0.00009290683,0.0004713098,0.00005018959,0.002343562],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008469917,"threshold_uncertainty_score":0.002833426,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0412699176269602,"score_gpt":0.3460541681797537,"score_spread":0.3047842505527935,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}