{"id":"W2085540265","doi":"10.1523/jneurosci.3560-05.2005","title":"N-Terminal Insertion and C-Terminal Ankyrin-Like Repeats of α-Latrotoxin Are Critical for Ca<sup>2</sup>+-Dependent Exocytosis","year":2005,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research","keywords":"Terminal (telecommunication); Exocytosis; Ankyrin repeat; Chemistry; Biophysics; Ankyrin; Biology; Membrane; Biochemistry; Computer science; Gene; Computer network","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001176242,0.0003039875,0.0002444126,0.00008836197,0.0001280066,0.0003094002,0.0001755977,0.0003130163,0.0005564157],"category_scores_gemma":[0.0002260073,0.0001454189,0.0002585516,0.0001123779,0.0003700952,0.0004224328,0.0002282991,0.0005255783,0.0003501275],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003653353,"about_ca_system_score_gemma":0.0001823195,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002790598,"about_ca_topic_score_gemma":0.0003172222,"domain_scores_codex":[0.9998531,0.00002573007,0.00002431525,0.0000285817,0.00004009273,0.00002822459],"domain_scores_gemma":[0.999723,0.00005394654,0.0001252584,0.00002492526,0.00002279922,0.00005010519],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007453375,0.000007076037,0.0001987117,0.00001482092,0.000002230552,0.00007542736,0.00000825979,0.00005446462,0.999097,0.0000458971,0.000004846034,0.0004167332],"study_design_scores_gemma":[0.00002036229,0.0001330662,0.009928111,0.000005013554,0.00001198941,0.0009214494,0.00002896959,0.001006464,0.9870007,0.00005500599,0.0008842072,0.000004687447],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954931,0.0005405491,0.003490407,0.00005459316,0.000008132925,0.00001613398,0.00007915989,0.00003297654,0.0002848765],"genre_scores_gemma":[0.9957603,0.0002212707,0.003010543,0.00003917265,0.000005410187,0.0000156622,0.0003479451,0.00001482373,0.0005848702],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005564157,"threshold_uncertainty_score":0.002650678,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02036701214977838,"score_gpt":0.2767318627689121,"score_spread":0.2563648506191337,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}