{"id":"W2085568870","doi":"10.1016/j.str.2006.03.003","title":"I Siah Substrate!","year":2006,"lang":"en","type":"letter","venue":"Structure","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada Research Chairs; University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Degron; Ubiquitin ligase; Ubiquitin-Protein Ligases; Ubiquitin; DNA ligase; Cell biology; Chemistry; Biology; Biophysics; Computational biology; Biochemistry; DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001681811,0.0003991421,0.0002530516,0.0002169679,0.0005831737,0.0008519694,0.0004254474,0.001586133,0.06237827],"category_scores_gemma":[0.0004515626,0.0001630374,0.0003686603,0.0001384953,0.00034089,0.0004924935,0.0004144548,0.002341355,0.03362501],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000689647,"about_ca_system_score_gemma":0.0002448451,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005969506,"about_ca_topic_score_gemma":0.0006674497,"domain_scores_codex":[0.9998875,0.00001421901,0.000005864654,0.00002596781,0.00003820899,0.00002824451],"domain_scores_gemma":[0.999911,0.00001593919,0.000008421084,0.00001789926,0.00001930335,0.0000274776],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007382568,0.00007323814,0.001276248,0.0002957428,0.0000317049,0.00489613,0.0000676497,0.0001233278,0.05177169,0.02791066,0.854201,0.05861443],"study_design_scores_gemma":[0.00005738793,0.00007736453,0.0009238987,0.00004093444,0.00001320543,0.004090337,0.0001021923,0.0002355123,0.03331476,0.005825192,0.9553047,0.00001447933],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"commentary","genre_scores_codex":[0.02894533,0.01327907,0.005736773,0.2739076,0.04727809,0.0002263174,0.002613603,0.001865795,0.6261474],"genre_scores_gemma":[0.1194076,0.005807349,0.003398765,0.06020099,0.00634285,0.0001419447,0.002556977,0.0001710409,0.8019724],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.06237827,"threshold_uncertainty_score":0.2086761,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007354333113989024,"score_gpt":0.2155821106078442,"score_spread":0.2082277774938552,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}