{"id":"W2085612389","doi":"10.1111/j.1750-3639.2000.tb00252.x","title":"Redox Regulation of Nuclear Factor Kappa B: Therapeutic Potential for Attenuating Inflammatory Responses","year":2000,"lang":"en","type":"review","venue":"Brain Pathology","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":147,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"National Heart, Lung, and Blood Institute","keywords":"Transcription factor; Reactive oxygen species; Oxidative stress; NFKB1; Lipid peroxidation; NF-κB; Endogeny; Cell biology; Chemistry; Enzyme; KEAP1; Signal transduction; Inflammation; Biochemistry; Biology; Immunology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003535158,0.0007291534,0.0008647166,0.001390162,0.0003029361,0.0006416396,0.0006020227,0.001115428,0.002996732],"category_scores_gemma":[0.0002332481,0.0001575892,0.0002976933,0.001174961,0.0004857134,0.0009498856,0.0003793072,0.001325391,0.002205244],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004045725,"about_ca_system_score_gemma":0.0004058378,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004324292,"about_ca_topic_score_gemma":0.0009715294,"domain_scores_codex":[0.9999201,0.0000160873,0.000009654956,0.00001700061,0.0000280476,0.000009133138],"domain_scores_gemma":[0.9999061,0.00003719651,0.00001362141,0.000004580425,0.00002255549,0.00001602126],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001884358,0.0001836143,0.0002534003,0.007351371,0.00007740193,0.0005792028,0.00009319578,0.0004085957,0.01865778,0.004300755,0.01939042,0.9485158],"study_design_scores_gemma":[0.00008195906,0.0003673514,0.001480735,0.001214259,0.00009910485,0.003931428,0.00009021594,0.0001744635,0.003397792,0.002977429,0.9861602,0.00002502742],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006285082,0.9959989,0.0005114723,0.0004391804,0.0003175642,0.000008574528,0.00001372532,0.0000188083,0.00206334],"genre_scores_gemma":[0.002877028,0.993829,0.000812227,0.0003705716,0.000345642,0.00001735917,0.00003331564,0.000003391723,0.001711457],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002996732,"threshold_uncertainty_score":0.01002508,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02737315607383443,"score_gpt":0.3086575860301383,"score_spread":0.2812844299563039,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}